Protein Alignment FRMD6 and Frmd6

DIOPT Version :10

• Sequence 1: NP_001253975.1
• Gene: FRMD6 / 122786
• HGNCID: 19839
• Length: 622
• Species: Homo sapiens
• Sequence 2: NP_001386220.1
• Gene: Frmd6 / 257646
• RGDID: 727810
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 622
• Identity: 578/622 - (92%)
• Similarity: 600/622 - (96%)
• Gaps: 0/622 - (0%)

Human     1 MNKLNFHNNRVMQDRRSVCIFLPNDESLNIIINVKILCHQLLVQVCDLLRLKDCHLFGLSVIQNN 65
            ||||.||||:||||||.||||||||:|::||||||||||||||||||||||||.|||||||||||
  Rat     1 MNKLTFHNNKVMQDRRRVCIFLPNDKSVSIIINVKILCHQLLVQVCDLLRLKDSHLFGLSVIQNN 65

Human    66 EHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGRLISDRAARY 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||.|||
  Rat    66 EHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGKLISDRIARY 130

Human   131 YYYWHLRKQVLHSQCVLREEAYFLLAAFALQADLGNFKRNKHYGKYFEPEAYFPSWVVSKRGKDY 195
            |||||||||||||||||||||||||||||||||||||||..|:|.|||||||||:||||||||||
  Rat   131 YYYWHLRKQVLHSQCVLREEAYFLLAAFALQADLGNFKRKVHHGDYFEPEAYFPAWVVSKRGKDY 195

Human   196 ILKHIPNMHKDQFALTASEAHLKYIKEAVRLDDVAVHYYRLYKDKREIEASLTLGLTMRGIQIFQ 260
            |||||||||:||||||||||:||||||||||||||:|||||||||||:|.|||||||||||||||
  Rat   196 ILKHIPNMHRDQFALTASEAYLKYIKEAVRLDDVAIHYYRLYKDKREVEGSLTLGLTMRGIQIFQ 260

Human   261 NLDEEKQLLYDFPWTNVGKLVFVGKKFEILPDGLPSARKLIYYTGCPMRSRHLLQLLSNSHRLYM 325
            ||:|||||||||||||||||||||||||||||||||||||:||||||.|||||||||||||||||
  Rat   261 NLEEEKQLLYDFPWTNVGKLVFVGKKFEILPDGLPSARKLVYYTGCPTRSRHLLQLLSNSHRLYM 325

Human   326 NLQPVLRHIRKLEENEEKKQYRESYISDNLDLDMDQLEKRSRASGSSAGSMKHKRLSRHSTASHS 390
            ||||||||:||.|||||||||||||||||||||||.|||||||||||||||||||||||||||||
  Rat   326 NLQPVLRHLRKQEENEEKKQYRESYISDNLDLDMDPLEKRSRASGSSAGSMKHKRLSRHSTASHS 390

Human   391 SSHTSGIEADTKPRDTGPEDSYSSSAIHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDLQDDEI 455
            ||||||||.||||||.||||.||.|.:||||||||||||||||||||||||||||||||.|||||
  Rat   391 SSHTSGIETDTKPRDPGPEDGYSGSVMHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDSQDDEI 455

Human   456 EMLVDDPRDLEQMNEESLEVSPDMCIYITEDMLMSRKLNGHSGLIVKEIGSSTSSSSETVVKLRG 520
            |||||||||||.|.||||||||:||||||:|||:|||||||||||||||.|||||||||||||||
  Rat   456 EMLVDDPRDLEPMTEESLEVSPEMCIYITQDMLLSRKLNGHSGLIVKEISSSTSSSSETVVKLRG 520

Human   521 QSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDEEGLYCN 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||:
  Rat   521 QSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDESGLYCD 585

Human   586 SCLAQQCINIQDAFPVKRTSKYFSLDLTHDEVPEFVV 622
            |||||||:|:.||||||||||||||||||||||||:|
  Rat   586 SCLAQQCVNMHDAFPVKRTSKYFSLDLTHDEVPEFLV 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FRMD6	NP_001253975.1	FERM_F1_FRMD6	15..120	CDD:340718	99/104 (95%)
		FERM_M	118..234	CDD:459788	105/115 (91%)
		FERM_C_FRMD1_FRMD6	227..335	CDD:270006	101/107 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..445		74/80 (93%)
Frmd6	NP_001386220.1	Ubl1_cv_Nsp3_N-like	15..120	CDD:475130	99/104 (95%)
		FERM_M	118..234	CDD:459788	105/115 (91%)
		FERM_C_FRMD1_FRMD6	227..335	CDD:270006	101/107 (94%)