Protein Alignment PLD4 and CG43345

DIOPT Version :10

• Sequence 1: NP_001295103.1
• Gene: PLD4 / 122618
• HGNCID: 23792
• Length: 513
• Species: Homo sapiens
• Sequence 2: NP_610096.1
• Gene: CG43345 / 35387
• FlyBaseID: FBgn0263050
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 439
• Identity: 172/439 - (39%)
• Similarity: 244/439 - (55%)
• Gaps: 49/439 - (11%)

Human    80 EHGSSPAWEPLEAEARQQRDSCQLVLVESIPQDLPSA--AGSPSAQPLGQAWLQLLDTAQESVHV 142
            |:|:||.  |:|...     .|||.||||:|..|..:  ...|.......||..||..|:.|:.:
  Fly    80 ENGNSPV--PVEKPL-----PCQLELVESLPLGLNYSQWQSHPQLSSTFDAWQLLLGRAKASLDI 137

Human   143 ASYYWSLTGPDIGVNDSSSQLGEALLQKLQQLL-----GR---NISLAVATSSPTLARTSTDLQV 199
            .|.:|:|.|.|  |||||:..|:   |..||||     ||   .:.:.|..|..:|  ...|.::
  Fly   138 VSPHWTLRGLD--VNDSSTGPGD---QLFQQLLSNGDAGRPKLRVRIVVNRSHDSL--WHADARI 195

Human   200 LAARGAHVRQVPMGRLTRGVLHSKFWVVDGRHIYMGSANMDWRSLTQVKELGAVIYNCSHLAQDL 264
            ||..||      ...:....||||.|:|||.|.|:|:|:||||||||.||||.:..||.|||.||
  Fly   196 LANYGA------ADVVGINFLHSKLWLVDGEHFYLGTASMDWRSLTQRKELGVLARNCPHLALDL 254

Human   265 EKTFQTYWVLGVPKAVLPKTWPQNFSSHFNRFQPF-------HGLFDGVPTTAYFSASPPALCPQ 322
            .|.|:.||.||..:  :||:||..:.:|.|:.:|.       |.:      .||.|.|||.|...
  Fly   255 GKIFKAYWYLGSNE--VPKSWPWIYHTHINQRRPLLLNINKKHTM------RAYLSTSPPELIAT 311

Human   323 GRTRDLEALLAVMGSAQEFIYASVMEYFPTTRFSHPPRYWPVLDNALRAAAFGKGVRVRLLVGCG 387
            ||||:|:|:|..:..|.:.||.|:|||.|..|.|:...||||:|||||.||..:||.:::|:...
  Fly   312 GRTRELDAILEAIDKATDVIYLSLMEYSPRLRRSNKLEYWPVIDNALRRAALERGVAIKVLISWW 376

Human   388 LNTDPTMFPYLRSLQALSNPAANVSVDVKVFIVPVGNH-SNIPFSRVNHSKFMVTEKAAYIGTSN 451
            ..:||:...:|||||||......|.:.::.|:||..|. ..|...|||.:.::||::.|:||||:
  Fly   377 KYSDPSEDHFLRSLQALDKITEGVDIQMRRFVVPTTNELERISGGRVNCNSYLVTDRVAFIGTSS 441

Human   452 WSEDYFSSTAGVGLVVTQSPGAQPAGATVQEQLRQLFERDWSSRYAVGL 500
            :|.::|:.:||:|||:..   .:....:::..|..:|.|||.|.||:.|
  Fly   442 FSGEHFTYSAGIGLVLQD---MEYNNNSLRTDLMAIFLRDWFSPYALPL 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLD4	NP_001295103.1	PLDc_vPLD4_1	105..274	CDD:197243	74/178 (42%)
		PLDc_vPLD4_2	311..497	CDD:197246	75/186 (40%)
CG43345	NP_610096.1	PHA02820	98..487	CDD:222934	162/412 (39%)