Protein Alignment Bub3 and Bub3

DIOPT Version :10

• Sequence 1: NP_033904.2
• Gene: Bub3 / 12237
• MGIID: 1343463
• Length: 326
• Species: Mus musculus
• Sequence 2: NP_477381.1
• Gene: Bub3 / 43490
• FlyBaseID: FBgn0025457
• Length: 326
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 195/322 - (60%)
• Similarity: 244/322 - (75%)
• Gaps: 3/322 - (0%)

Mouse     6 EFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHA 70
            |||||.||||.||:|||.|.::|::..||||.::|.||||||.:|.|:.....:|||||.|..|.
  Fly     5 EFKLNNPPEDLISAVKFGPKSNQYMAASSWDGTLRFYDVPANQLRQKFVQDAPLLDCAFMDIVHV 69

Mouse    71 WSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPRTPCNAGTFS 135
            .||.||:||::.|:||..|:::|.|:.||||||:...||.::|||||.||||||.|.....|||.
  Fly    70 VSGSLDNQLRLFDVNTQAESIIGAHEEPIRCVEHAEYVNGILTGSWDNTVKLWDMREKRCVGTFE 134

Mouse   136 QPE-KVYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSI 199
            |.. |||::||..::::|.|:.|:||:||||.|.....:|||||||||||||.||||:|||:|||
  Fly   135 QNNGKVYSMSVIDEKIVVATSDRKVLIWDLRKMDSYIMKRESSLKYQTRCIRLFPNKEGYVMSSI 199

Mouse   200 EGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPF 264
            ||||||||||..||||::|:||||||.:|.||||||||||:||||::.|||||||||.|||||.|
  Fly   200 EGRVAVEYLDHDPEVQRRKFAFKCHRNREQNIEQIYPVNALSFHNVYQTFATGGSDGIVNIWDGF 264

Mouse   265 NKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDTEH--PEDGIFIRQVTDAETKPK 324
            |||||||||.|.|||::|.||:||:.|||..||:.::.:|..  |...|:||..||.|||.|
  Fly   265 NKKRLCQFHEYDTSISTLNFSSDGSALAIGCSYLDQLPETPATVPHPAIYIRYPTDQETKQK 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bub3	NP_033904.2	WD 1	5..43		21/36 (58%)
		WD40	<11..296	CDD:441893	177/285 (62%)
		WD40 repeat	17..54	CDD:293791	20/36 (56%)
		WD 2	46..83		17/36 (47%)
		WD40 repeat	60..94	CDD:293791	17/33 (52%)
		WD 3	86..124		21/37 (57%)
		WD40 repeat	99..134	CDD:293791	20/34 (59%)
		WD 4	128..163		14/35 (40%)
		WD40 repeat	141..175	CDD:293791	13/33 (39%)
		WD40 repeat	182..222	CDD:293791	31/39 (79%)
		WD 5	223..262		30/38 (79%)
		WD40 repeat	237..274	CDD:293791	30/36 (83%)
Bub3	NP_477381.1	WD40	16..262	CDD:475233	150/246 (61%)
		WD40 repeat	16..53	CDD:293791	20/36 (56%)
		WD40 repeat	59..93	CDD:293791	17/33 (52%)
		WD40 repeat	98..134	CDD:293791	21/35 (60%)
		WD40 repeat	141..175	CDD:293791	13/33 (39%)
		WD40 repeat	182..222	CDD:293791	31/39 (79%)
		WD40 repeat	237..283	CDD:293791	35/45 (78%)