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Protein Alignment Smyd1 and Smyd3

DIOPT Version :9

Sequence 1:	NP_001153599.1	Gene:	Smyd1 / 12180	MGIID:	104790	Length:	490	Species:	Mus musculus
Sequence 2:	NP_524768.2	Gene:	Smyd3 / 44554	FlyBaseID:	FBgn0011566	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	121/492 - (24%)
Similarity:	209/492 - (42%)	Gaps:	76/492 - (15%)

- Green bases have known domain annotations that are detailed below.

Mouse     2 TIGSMENVEVFTS----EGKGRGLK-ATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEK 61
            |:||..:.....:    ..|.:.|| ...:......|..|:.::.|:........|..|.: ..|
  Fly     5 TVGSSRSATTSATASACSSKSKNLKNPAPQIKRGQRILTEKPFAFVLKSQYRLERCDNCLE-ATK 68

Mouse    62 LHRCGQCKFAHYCDRTCQKDAWLNHKNECAAIKK-YGKVPNENIRLAARIMWRVEREGTGL---- 121
            :.:|..|::..||.|:||..||..||:||..:|| :.:|..:..|:..|::.|:|..|..:
  Fly    69 VLKCSNCRYVSYCHRSCQMQAWGQHKHECPFLKKVHPRVVPDAARMLCRLILRLEHGGDLIRGYY 133

Mouse   122 TEGCLVSVDDLQNHVEHFGEEEQKELRVD-------VDTFLQYWPPQSQQFSMQYISHIFGVINC 179
            ||.......||   :.|:.|.:...:|::       |.|.:....|.:.....:.:| |:|.:..
  Fly   134 TEHGSRKFRDL---MSHYAEIKNDPMRLEHLDSLHAVLTDMMAESPSTVPNKTELMS-IYGRLIT 194

Mouse   180 NGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISE 244
            |||.:.|.. :.::...|:..:.:.:|.|.||....| .||.      .|.....::..|    :
  Fly   195 NGFNILDAE-MNSIATAIYLGVSITDHSCQPNAVATF-EGNE------LHVHAIEDMECL----D 247

Mouse   245 GEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLFLAAKEDPKPSQEVVKEM---- 305
            ..::.:||||.|:..|:||..||:.|||.|.|..|             .|.|.|:|::..:
  Fly   248 WSKIFISYIDLLNTPEQRRLDLKEHYYFLCVCSKC-------------TDAKESKEMLAALCPNR 299

Mouse   306 -----IQFSKDTLEKIDKARSEGL---YHEVVKL----------------CRECLEKQEPVFADT 346
                 |...::...:.|...|..|   ::|.:.|                |:.||:||..||...
  Fly   300 NCGAGISVDRNNCPRCDAGISPKLRNAFNEAMTLTRHNLENMKDVAYLDVCKVCLDKQTGVFHPL 364

Mouse   347 NLYVLRLLSIASEVLSYLQAYEEASHYARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHAGHIEV 411
            |::.::.|..|.|....:..:.:|..|.:|::.|:.|.:...|..||:..|:.|....:.||.:.
  Fly   365 NVWYVKTLDAAFEAAIEVGKWSDALDYGQRLLPGFRKYHGPWNPLLGLLHMKLGKIQLYEGHSKE 429

Mouse   412 GHGMICKAYAILLVTHGPSHP-ITKDLEAMRMQTEME 447
            ....:.:|..||.||||..|. :|:.|..:.:|...|
  Fly   430 ALHHLEEAQRILTVTHGRDHRLLTEQLYMLVLQARQE 466

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.