back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd1 and Smyd4-4

DIOPT Version :9

Sequence 1:	NP_001153599.1	Gene:	Smyd1 / 12180	MGIID:	104790	Length:	490	Species:	Mus musculus
Sequence 2:	NP_610730.1	Gene:	Smyd4-4 / 36299	FlyBaseID:	FBgn0027495	Length:	573	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	76/335 - (22%)
Similarity:	121/335 - (36%)	Gaps:	92/335 - (27%)

- Green bases have known domain annotations that are detailed below.

Mouse     9 VEVFTSEGKGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQE--KLHRCGQCKFA 71
            :|:..:..:||.:...::....|::..|..:.:.:...:....|.|| ||:.  .|..|..|...
  Fly   187 LELRETAAEGRFVVTNRDLAVGDLVSVEEPFCSTLLTPMRYIRCATC-KRENYLTLIPCDSCCST 250

Mouse    72 HYCDRTCQKDAWLN-HKNECAAIKKYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDL--- 132
            .:|...|:..|... |:.||..|....::.|:...:|.|.        |.:......|:::|
  Fly   251 MFCSEECKSIAMQTYHRYECPIIDFLNRMFNKIHCIALRT--------TLVALNIFPSIEELIDF 307

Mouse   133 ----QNH--------------VEHF----GEEEQKELRVDVDTF-------------LQYWPPQS 162
                ||.              .||:    |....:.||...|.|             ::|.|.:
  Fly   308 CEQEQNQDKCAFDLNYNELTPEEHYRAIHGLVTNQHLRSVSDLFQRSVVCAVLKHFIIEYTPVK- 371

Mouse   163 QQFSMQYISHIFGV---------------INCNGFTLSDQ----RGLQAVGVGIFPNLGLVNHDC 208
                 :|:....||               .|.:|..|.:|    :..|....|.:..|.|:||.|
  Fly   372 -----EYLGGEEGVNFFTDLLFRHLQTSPSNMHGIDLVEQVNETKDDQTHSSGAYAFLSLINHSC 431

Mouse   209 WPNCTVIFNNGNHEAVKS-MFHTQMRIELRALGKISEGEELTVSY-IDFLHLSEERR-RQLKKQY 270
            .||...|:     |..|: ||         .|..|..|..|..:| ..|...|:|:| ::|..||
  Fly   432 APNTVRIY-----EGTKAYMF---------VLRPIKAGNVLYDNYGAHFAICSKEQRLKRLSLQY 482

Mouse   271 YFDCSCEHCQ 280
            .|||.||.|:
  Fly   483 RFDCKCEGCE 492

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.