Protein Alignment Bmp8b and scw

DIOPT Version :10

• Sequence 1: NP_031585.2
• Gene: Bmp8b / 12164
• MGIID: 107335
• Length: 399
• Species: Mus musculus
• Sequence 2: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 426
• Identity: 120/426 - (28%)
• Similarity: 194/426 - (45%)
• Gaps: 88/426 - (20%)

Mouse    17 VLGGGHLSHPPHVFPQRRLGVREPRDMQREIREVLGLPGRPRSRAPVGAAQQP---ASAPLFMLD 78
            |....|:..|.:   |:|     |...|.|:.::|.|..|||.:|      :|   .||..|:|:
  Fly    20 VTTNNHIEMPIY---QKR-----PLSEQMEMIDILDLGDRPRRQA------EPNLHNSASKFLLE 70

Mouse    79 LYRAMTDDSGGGTPQPHL-----------------DRADL-----IMSFVNIVERDRTLGYQEPH 121
            :|..:::|.   .|:..|                 ||.::     |::|.:.::.::.....:.|
  Fly    71 VYNEISEDQ---EPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLKPEQLDNELDMH 132

Mouse   122 WKEFHFDLTQIPAGEAVTAAEFRIYKEPSTHPLNTTLHISMFEVVQEHSNRESDLFFLDLQTLR- 185
               ..|:...:|...::..|..||||:||.........:|::   ::..||: |..:..|.::.
  Fly   133 ---ITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVSVY---RKLDNRQ-DFSYRILGSVNT 190

Mouse   186 -SGDEGWLVLDITAASDRWLLNHHKDLGLRLYVETEDGHS-IDPGLAGLLGRQAPR-SRQPFMVG 247
             |...|||..::|.....||  |:|.|..|..:....|.| :....|||:..||.| |.:||:||
  Fly   191 TSSQRGWLEFNLTDTLRYWL--HNKGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLEPFIVG 253

Mouse   248 FFRANQSPVRAP--RTARPLKKKQLNQINQLPHSNKHLGILDDGHGS------------HGREVC 298
            :|...:..|:..  |..|.|:|::.                  |.||            ...:.|
  Fly   254 YFNGPELLVKIQKLRFKRDLEKRRA------------------GGGSPPPPPPPPVDLYRPPQSC 300

Mouse   299 RRHELYVSFRDLGWLDSVIAPQGYSAYYCAGECIYPLNSCMNSTNHATMQALVHLMKPDIIPKVC 363
            .|....|.|::|...:.||||:.:.||:|.|.|.:||.:.||:||||.:|.|:||.:|. :||.|
  Fly   301 ERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPH-LPKPC 364

Mouse   364 CVPTELSAISLLYYDRNNNVILRRERNMVVQACGCH 399
            ||||.|.||::|.|...:.:.|.:.:..|.:.||||
  Fly   365 CVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bmp8b	NP_031585.2	TGFb_propeptide	32..248	CDD:459906	62/244 (25%)
		TGF_beta_SF	295..399	CDD:477357	43/103 (42%)
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	59/232 (25%)
		TGF_beta_BMP5_like	299..400	CDD:381639	43/101 (43%)