Protein Alignment Bmp7 and scw

DIOPT Version :9

• Sequence 1: NP_031583.2
• Gene: Bmp7 / 12162
• MGIID: 103302
• Length: 430
• Species: Mus musculus
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 439
• Identity: 136/439 - (30%)
• Similarity: 212/439 - (48%)
• Gaps: 77/439 - (17%)

Mouse    21 LFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPR----PHLQGKHNSAPM 81
            ||...||....:.:|.:......:|..|:     |.|::.||.|..|||    |:|   ||||..
  Fly    10 LFYAASATTYVTTNNHIEMPIYQKRPLSE-----QMEMIDILDLGDRPRRQAEPNL---HNSASK 66

Mouse    82 FMLDLYNAMAVEESGPDGQGFSYPYKAVF------STQGPPLASLQDSHFLTDADMVMSFVNLV- 139
            |:|::||.:: |:..|         |.|.      |.....|.|.:|...:...:.:::|.:.:
  Fly    67 FLLEVYNEIS-EDQEP---------KEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLK 121

Mouse   140 --EHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKD-YIRERFDNETFQITVYQVL---Q 198
              :.|.|.      .....|:.:.:|...::..|..||||. .:.:|..|  |.::||:.|   |
  Fly   122 PEQLDNEL------DMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRAN--FTVSVYRKLDNRQ 178

Mouse   199 EHSGRESDLFLLDSRTIWASEEGWLVFDITATSNHWVVNPRHNLGLQ----LSVETLDGQSINPK 259
            :.|.|     :|.|....:|:.|||.|::|.|..:|:    ||.|||    |.:...|.| ::..
  Fly   179 DFSYR-----ILGSVNTTSSQRGWLEFNLTDTLRYWL----HNKGLQRRNELRISIGDSQ-LSTF 233

Mouse   260 LAGLIGRHGPQ----NKQPFMVAFFKATE--VHLRSIRSTGG--KQRSQNRSKTPKNQEALRMAS 316
            .|||:   .||    :.:||:|.:|...|  |.::.:|....  |:|:...|..|.....:.:..
  Fly   234 AAGLV---TPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYR 295

Mouse   317 VAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTL 381
                    ..|:|::....|.|::|...:|:|||:.:.||:|.|.|.|||.:.||||||||||||
  Fly   296 --------PPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTL 352

Mouse   382 VHFINPDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH 430
            :|...|. :|||||.||.|.||::|.:.:...:.|.||:..|.:.||||
  Fly   353 MHLKQPH-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bmp7	NP_031583.2	TGFb_propeptide	35..279	CDD:395559	74/268 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	290..310		5/21 (24%)
		TGF_beta_BMP7	324..430	CDD:381667	48/105 (46%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	71/248 (29%)
		TGFB	300..400	CDD:214556	47/100 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.870