Protein Alignment ASCL4 and tx

DIOPT Version :10

• Sequence 1: NP_982260.3
• Gene: ASCL4 / 121549
• HGNCID: 24311
• Length: 172
• Species: Homo sapiens
• Sequence 2: NP_524516.2
• Gene: tx / 43190
• FlyBaseID: FBgn0288888
• Length: 384
• Species: Drosophila melanogaster
• Alignment Length: 186
• Identity: 44/186 - (23%)
• Similarity: 65/186 - (34%)
• Gaps: 74/186 - (39%)

Human    51 RSGCARGWQY----------------------LPVPLDSAFEPA--------------------F 73
            ::..|||.:|                      ..:.||...|||                    :
  Fly    30 KTASARGEKYSLRQKRQKRGSNEDGESANLADFQLELDPIAEPASKSRKNAPTKSKTKAPPLSKY 94

Human    74 LRK-RNERERQRVRCVNEGYARLRDHLPREL-------ADKRLSKVETLRAAIDYI--------- 121
            .|| .|.|||.|:|.:|..:..||..:|..:       .:::|:|:.|||.|:.||
  Fly    95 RRKTANARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIRD 159

Human   122 ---------KHLQELLERQA-WGLEGAAGA-----VPQRRAECNSDGESKASSAPS 162
                     :.|:|...|:| ..||....|     ||..:....:.|..|.|||.|
  Fly   160 PSYESEFIGECLEESANREARVDLEANEEAEVELPVPVAKKPAKTKGSGKKSSAAS 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASCL4	NP_982260.3	bHLH_SF	66..129	CDD:469605	26/108 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..172		6/19 (32%)
tx	NP_524516.2	bHLH_TS_taxi_Dei	95..157	CDD:381437	20/61 (33%)