Protein Alignment ASCL4 and Fer2

DIOPT Version :10

• Sequence 1: NP_982260.3
• Gene: ASCL4 / 121549
• HGNCID: 24311
• Length: 172
• Species: Homo sapiens
• Sequence 2: NP_001287359.1
• Gene: Fer2 / 41961
• FlyBaseID: FBgn0038402
• Length: 283
• Species: Drosophila melanogaster
• Alignment Length: 320
• Identity: 69/320 - (21%)
• Similarity: 113/320 - (35%)
• Gaps: 82/320 - (25%)

Human  1165 PHCEALKSLTMQVLNSMAAFIALPSILQRILQDPIYGK-GKLGEIQGLILGMLDT------FNY- 1221
            |..:.:|.|....|.....|:  .:..:.:.|:.:... .|.|||...:: |.|.      |.:
  Fly   222 PRAQRMKELGESGLKYTNVFV--KNFGEHLDQEKLSAMFSKFGEITSAVV-MTDAQGKPKGFGFV 283

Human  1222 ---EQTLLETTASLLNQ------DLHWSLCNLRASVSRGLNPKQDYCSICLQQYKRRQ------- 1270
               :|.........||.      |...|:|..:....|....|:.|.::..::.:|.|
  Fly   284 AFADQDAAGQAVEKLNDSILEGTDCKLSVCRAQKKSERSAELKRKYEALKQERVQRYQGVNLYVK 348

Human  1271 EMADEIIVFSCGHLYHSF-CLQSKECTLEVEGQTRWACHKCSSSNKAGKLSENPSENKKGRITSS 1334
            .:.:::........:.|| .:.|.:..::..|:::.....|         .|.| |.....:|..
  Fly   349 NIEEDLNDDGLRDHFSSFGTITSAKVMVDENGRSKGFGFVC---------FEKP-EEATAAVTDM 403

Human  1335 QVKM---SPSY---HQSKGDPPARKANSEPVLDPQQMQAFDQLCRLYRGSSRLALLTELSQ---- 1389
            ..||   .|.|   .|.|.|..|:.|:       |.||....| |:.:.:|.:..:|:|.|
  Fly   404 NSKMIGAKPLYVALAQRKEDRRAQLAS-------QYMQRLATL-RMGQQASGVPAMTQLYQPGQQ 460

Human  1390 --------NRGGDSCRPFAGPQS----GPAFNSVFQKENF------QLQLAP-----PPV 1426
                    |..|   ||...|||    ||....|||.:.|      |.|:.|     ||:
  Fly   461 GYFVPNPMNAQG---RPGFQPQSAQIRGPPGQRVFQNQMFMQYPFNQRQVYPQQQGRPPM 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASCL4	NP_982260.3	bHLH_SF	66..129	CDD:469605
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..172
Fer2	NP_001287359.1	bHLH_SF	144..216	CDD:469605