Protein Alignment ASCL4 and l(1)sc

DIOPT Version :10

• Sequence 1: NP_982260.3
• Gene: ASCL4 / 121549
• HGNCID: 24311
• Length: 172
• Species: Homo sapiens
• Sequence 2: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 137
• Identity: 42/137 - (30%)
• Similarity: 61/137 - (44%)
• Gaps: 47/137 - (34%)

Human    76 KRNERERQRVRCVNEGYARLRDHLPREL----------ADKRLSKVETLRAAIDYIKHLQELLER 130
            :||.|||.||:.||.|:..||.|||:.:          :.|:||||:|||.|::||:.||::|:
  Fly    87 RRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLD- 150

Human   131 QAWGLEGAAGA---VPQRRAECNSDGES----------------------------KASSAPSPS 164
                 :|.|.:   :.....|.::||.|                            .||..||.|
  Fly   151 -----DGTASSTRHIYNSADESSNDGSSYNDYNDSLDSSQQFLTGATQSAQSHSYHSASPTPSYS 210

Human   165 SEPEEGG 171
            .....||
  Fly   211 GSEISGG 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASCL4	NP_982260.3	bHLH_SF	66..129	CDD:469605	28/62 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..172		11/56 (20%)
l(1)sc	NP_476623.1	bHLH_TS_dAS-C_like	94..149	CDD:381587	23/54 (43%)