Protein Alignment ASCL4 and sc

DIOPT Version :10

• Sequence 1: NP_982260.3
• Gene: ASCL4 / 121549
• HGNCID: 24311
• Length: 172
• Species: Homo sapiens
• Sequence 2: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Alignment Length: 173
• Identity: 57/173 - (32%)
• Similarity: 88/173 - (50%)
• Gaps: 24/173 - (13%)

Human     6 PAERLALPYSLRTAPLGVPGTLPGLPRR-DPLRVALRLDAACWEWARSGCARGWQYLPVPLDSAF 69
            ||....:|...:..|   .||:|...|: .|..:||   ..|.| :.|..:.|....|..:|
  Fly    42 PAPSPLIPGGNQNQP---AGTMPIKTRKYTPRGMAL---TRCSE-SVSSLSPGSSPAPYNVD--- 96

Human    70 EPAFLRKRNERERQRVRCVNEGYARLRDHLPREL-----------ADKRLSKVETLRAAIDYIKH 123
            :...:::||.|||.||:.||..:||||.|:|:.:           ..|::|||:|||.|::||:.
  Fly    97 QSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRR 161

Human   124 LQELLERQAWGLE-GAAGAVPQRRAECNSDGESKASSAPSPSS 165
            ||:|::....|.. ||..||.|.:. |..:..|.:||:.:.||
  Fly   162 LQDLVDDLNGGSNIGANNAVTQLQL-CLDESSSHSSSSSTCSS 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASCL4	NP_982260.3	bHLH_SF	66..129	CDD:469605	29/73 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..172		7/22 (32%)
sc	NP_476803.1	bHLH_TS_dAS-C_like	100..166	CDD:381587	27/65 (42%)