Protein Alignment AEBP2 and MET32

DIOPT Version :10

• Sequence 1: NP_001107648.1
• Gene: AEBP2 / 121536
• HGNCID: 24051
• Length: 517
• Species: Homo sapiens
• Sequence 2: NP_010539.1
• Gene: MET32 / 851840
• SGDID: S000002661
• Length: 191
• Species: Saccharomyces cerevisiae
• Alignment Length: 86
• Identity: 25/86 - (29%)
• Similarity: 36/86 - (41%)
• Gaps: 13/86 - (15%)

Human   273 NSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNT----PSTSQSWLQRHMLTHSGDKPFKCVVG 333
            |..|.|......:.::.|.|.:.|      |..|.    |.:|:|..|... ..:|:|.|||  .
Yeast    46 NKKPALIPAENGVDINSQGGNIKV------KKENALPKPPKSSKSKPQDRR-NSTGEKRFKC--A 101

Human   334 GCNASFASQGGLARHVPTHFS 354
            .|:..|:....|.||..|||:
Yeast   102 KCSLEFSRSSDLRRHEKTHFA 122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AEBP2	NP_001107648.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..229
		Interaction with RBBP4	209..294		5/20 (25%)
		COG5048	<215..>339	CDD:227381	18/69 (26%)
		C2H2 Zn finger	266..286	CDD:275368	3/12 (25%)
		C2H2 Zn finger	297..322	CDD:275368	6/28 (21%)
		C2H2 Zn finger	330..352	CDD:275368	6/21 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	352..394		2/3 (67%)
		Interaction with SUZ12. /evidence=ECO:0000269|PubMed:29499137	407..478
		Important for nucleosome binding activity of the PRC2 complex. /evidence=ECO:0000269|PubMed:29499137	495..517
MET32	NP_010539.1	COG5048	<41..191	CDD:227381	25/86 (29%)
		C2H2 Zn finger	100..120	CDD:275368	6/21 (29%)
		C2H2 Zn finger	128..144	CDD:275368