DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bmp1 and CG15253

DIOPT Version :9

Sequence 1:	NP_001346950.1	Gene:	Bmp1 / 12153	MGIID:	88176	Length:	991	Species:	Mus musculus
Sequence 2:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	85/248 - (34%)
Similarity:	115/248 - (46%)	Gaps:	22/248 - (8%)

- Green bases have known domain annotations that are detailed below.

Mouse    89 PSIKAAGNSSALGG--QGTSGQPQRESRGRWRGRPRSRRAATSRPERVWPDGVIPFVIGGNFTGS 151
            |||:...:.....|  :|.. .|...||..||..       |.|    ||:.:|.:.|.......
  Fly    21 PSIRIETDPELTAGYIEGDM-VPSGSSRNIWRNE-------TYR----WPNRIIYYHINSYIDEE 73

Mouse   152 QRAVFRQAMRHWEKHTCVTFLE-RTDEDSYIVFTYRPCGCCSYVGRRGG----GPQAISIGKNCD 211
            .|.....|::..|..:|:||.| .||:..|:..|....||.||:|....    ..|...||..|.
  Fly    74 HRNHIVSAIQKIESISCLTFKEATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCF 138

Mouse   212 KFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMH 276
            :...:|||..|.:||:|:.:..|||.:|.||.|||..|.|:||.|...:.|...||.||:.|:||
  Fly   139 RLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMH 203

Mouse   277 YARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGE 329
            |....||:. ...||:...|  |.:..||||..||:.||.:...:||||...|
  Fly   204 YGPYAFSKN-GERTILALEE--GKEDVIGQRLELSETDIRKLNAIYKCPTVKE 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bmp1	NP_001346950.1	ZnMc_BMP1_TLD	126..325	CDD:239808	72/203 (35%)
		CUB	327..436	CDD:278839	1/3 (33%)
		CUB	440..549	CDD:278839
		FXa_inhibition	560..592	CDD:317114
		CUB	596..705	CDD:278839
		FXa_inhibition	712..747	CDD:317114
		CUB	752..861	CDD:278839
		CUB	865..978	CDD:278839
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	72/201 (36%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	66/189 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810