Protein Alignment SDR9C7 and Rdh1

DIOPT Version :10

• Sequence 1: NP_683695.1
• Gene: SDR9C7 / 121214
• HGNCID: 29958
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Alignment Length: 198
• Identity: 53/198 - (26%)
• Similarity: 88/198 - (44%)
• Gaps: 26/198 - (13%)

Human    26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRD-----TSYRLQTTLLDVTKSES 85
            |...:||.::|.|...|.::..||..|..||......:|.::|     .:..:.:..||::..:|
  Fly    44 KVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLSSLDS 108

Human    86 IKAAAQWVRDKVGEQGLWALVNNAGV-GLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVK 149
            |:......:.:  :..|..|:||||| ..|    :.||||.:...:.||.:|...:|..:|.::|
  Fly   109 IRKFVDGFKKE--QPKLHVLINNAGVMRCP----KTLTKDGYELQLGVNHIGHFLLTNLLLDVLK 167

Human   150 R-ARGRVVNMSS---SGGRVAVI----------GGGYCVSKFGVEAFSDSIRRELYYFGVKVCII 200
            . |..|:|.:||   :.|.:.|.          |..|..||.....|:..:.:.|...||.|..:
  Fly   168 NSAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNAL 232

Human   201 EPG 203
            .||
  Fly   233 HPG 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SDR9C7	NP_683695.1	type2_17beta_HSD-like_SDR_c	26..302	CDD:187665	53/198 (27%)
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	53/198 (27%)