Protein Alignment Bax and Buffy

DIOPT Version :10

• Sequence 1: XP_011249082.1
• Gene: Bax / 12028
• MGIID: 99702
• Length: 221
• Species: Mus musculus
• Sequence 2: NP_523702.1
• Gene: Buffy / 36251
• FlyBaseID: FBgn0040491
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 198
• Identity: 40/198 - (20%)
• Similarity: 71/198 - (35%)
• Gaps: 52/198 - (26%)

Mouse    16 SEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQ------PPQDASTKKLSECLRRIGDELDSNM 74
            ::.|:..|..|...:|:.|..|......:|.|::      .......:.:...::.:||
  Fly    86 AQDIISQGRCLCGHYIKRRLRRSGLFNKKLGLQRIRSILGSTSMGIVRDVFPAVQVLGD------ 144

Mouse    75 ELQRMIADVDTDSPREV------------------------FFRVAADMFADGNFNWGRVVALFY 115
            ||:||...:.....|::                        .|||        ...|.:|::||.
  Fly   145 ELERMHPRIYNGVARQICRNPGGEFHTPDAVSLLLGAVGRELFRV--------EITWSKVISLFA 201

Mouse   116 FASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGW------VRPLSEDLNKLH--RL 172
            .|..|.:..:....||.:..:|....:.:.:.|:.||.:.|||      |.|.:..||.|.  .|
  Fly   202 IAGGLSVDCVRQGHPEYLPKLMESVSEVIEDELVPWINENGGWSGINTHVLPTTNSLNPLEWTTL 266

Mouse   173 ALG 175
            .:|
  Fly   267 VIG 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bax	XP_011249082.1	bcl-2	5..>158	CDD:273308	31/171 (18%)
Buffy	NP_523702.1	Bcl-2_like	99..250	CDD:132900	30/164 (18%)