Protein Alignment CLN3 and YHC3

DIOPT Version :10

• Sequence 1: XP_054170579.1
• Gene: CLN3 / 1201
• HGNCID: 2074
• Length: 489
• Species: Homo sapiens
• Sequence 2: NP_012476.1
• Gene: YHC3 / 853387
• SGDID: S000003595
• Length: 408
• Species: Saccharomyces cerevisiae
• Alignment Length: 430
• Identity: 160/430 - (37%)
• Similarity: 210/430 - (48%)
• Gaps: 80/430 - (18%)

Human    92 FWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRFDCNSVSTAAVLLADI 156
            |||.||.||..|||:||||.||:              |||              :..:.||||||
Yeast    12 FWLFGLINNVLYVVILSAAVDIV--------------GPT--------------LPKSLVLLADI 48

Human   157 LPTLVIKLLAPLGLHLLPYSPRV--LVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVT 219
            .|:|.|||.:|..:..:.||.|:  |::..| .|.| ||:|. ::...|.|:.|||||||.||||
Yeast    49 FPSLAIKLCSPFFIDRIKYSYRIWSLITMSC-LGMF-LVSFK-NLFVCLLGISFASISSGFGEVT 110

Human   220 FLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLL--- 281
            ||.||.:|.:..::.|||||||||::|..||:.||.....|.:..|.:..:.......||.|
Yeast   111 FLQLTHYYKQISLNGWSSGTGGAGIIGGASYMFLTSIFKVPVKLTLLVFSLLPFAFLFYFKLESN 175

Human   282 ---LTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGSSSSLSL------------RERWTVFKG 331
               ||....|.   .:|||.....|.     |.:...:::|.||            |.|..||.
Yeast   176 DTNLTYQSLQQ---IDEAEDDQLVPF-----PVAFTHTNASQSLYSTRQHILQTVKRLRRLVFP- 231

Human   332 LLWYIVPLVVVYFAEYFINQGLFELL--------------FFWNTSLSHAQQYRWYQMLYQAGVF 382
               |:|||..||..||.|||.:...|              ||::   .:...|..|..|||.|||
Yeast   232 ---YMVPLTTVYLFEYLINQAVAPTLLFPINGDERSKSMPFFFH---KYRDIYVTYGTLYQLGVF 290

Human   383 ASRSSLRCCRIRFTWALALLQCLNLVFLLADVWFGFLPSIYLVFLIILYEGLLGGAAYVNTFHNI 447
            .|||.....|:|..:.||.||.:||...:...||....|.:.|.::|.|||.||||:|||||.||
Yeast   291 ISRSFGHLMRMRSLYILAFLQGVNLCITVLQSWFYVTHSPWAVMILIFYEGFLGGASYVNTFLNI 355

Human   448 ALETSDEHREFAMAATCISDTLGISLSGLLALPLHDFLCQ 487
            ..:...:..||||.|..|:|:.|:.|:.||.|.|...||:
Yeast   356 LEQEDPDETEFAMGAVSIADSFGVFLAALLGLGLEPKLCR 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLN3	XP_054170579.1	CLN3	90..488	CDD:460570	160/430 (37%)
YHC3	NP_012476.1	CLN3	11..396	CDD:460570	160/430 (37%)