Protein Alignment CLN3 and Cln3

DIOPT Version :10

• Sequence 1: XP_054170579.1
• Gene: CLN3 / 1201
• HGNCID: 2074
• Length: 489
• Species: Homo sapiens
• Sequence 2: NP_001006972.1
• Gene: Cln3 / 293485
• RGDID: 1359537
• Length: 438
• Species: Rattus norvegicus
• Alignment Length: 421
• Identity: 362/421 - (85%)
• Similarity: 388/421 - (92%)
• Gaps: 0/421 - (0%)

Human    68 EETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTP 132
            |||..||:.|.||:....||||||||:||||||||||||||||||||..::.|||||||:|||||
  Rat    17 EETDSEPQTPPLDNLSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGPTP 81

Human   133 IPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSH 197
            :||||||||||||:|||||||||||||||||||||||||||||||||||||:|:||||||||||.
  Rat    82 MPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQ 146

Human   198 SVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQ 262
            |||.||||||.||||||||||||||||||||.|||||||||||||||||:||||||||||||||.
  Rat   147 SVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQH 211

Human   263 TLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGSSSSLSLRERWT 327
            |||||||||.|:||||||||||||..||||::|||:|||||||.||.|||:||:|..|||:||||
  Rat   212 TLLSMLGIPVLMLASYFLLLTSPEPLDPGGQDEAETAARQPLIGTETPESRPGTSWDLSLQERWT 276

Human   328 VFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQMLYQAGVFASRSSLRCCR 392
            ||||||.||:|||:||||||||||||||||||.||||||||||||||||||||||||||||:|||
  Rat   277 VFKGLLRYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCR 341

Human   393 IRFTWALALLQCLNLVFLLADVWFGFLPSIYLVFLIILYEGLLGGAAYVNTFHNIALETSDEHRE 457
            |||||.|||||||||.||||||...|||||||:|::|||||||||||||||||||||||||:|||
  Rat   342 IRFTWILALLQCLNLAFLLADVCLTFLPSIYLIFIVILYEGLLGGAAYVNTFHNIALETSDKHRE 406

Human   458 FAMAATCISDTLGISLSGLLALPLHDFLCQL 488
            |||.|.||||||||||||:||||||||||.|
  Rat   407 FAMEAACISDTLGISLSGVLALPLHDFLCHL 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLN3	XP_054170579.1	CLN3	90..488	CDD:460570	349/397 (88%)
Cln3	NP_001006972.1	CLN3	39..437	CDD:460570	349/397 (88%)