back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CLN3 and Cln3

DIOPT Version :10

Sequence 1:	XP_054170579.1	Gene:	CLN3 / 1201	HGNCID:	2074	Length:	489	Species:	Homo sapiens
Sequence 2:	NP_034037.3	Gene:	Cln3 / 12752	MGIID:	107537	Length:	438	Species:	Mus musculus

Alignment Length:	488	Identity:	376/488 - (77%)
Similarity:	396/488 - (81%)	Gaps:	51/488 - (10%)

- Green bases have known domain annotations that are detailed below.

Human     1 MGGCAGSRRRFSDSEGEYSRPPSWNDHLWLAAHLRGMRADSAPGGHARSGRAPESRWGSCPLLAL 65
            ||..|||.||..|||
Mouse     1 MGSSAGSWRRLEDSE-------------------------------------------------- 15

Human    66 PGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGP 130
             .|||..||:.|.||.:...||||||||:||||||||||||||||||||..::.|||||||:|||
Mouse    16 -REETDSEPQAPRLDSRSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGP 79

Human   131 TPIPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAF 195
            ||.||||||||||||:|||||||||||||||||||||||||||||||||||||:|:|||||||||
Mouse    80 TPTPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAF 144

Human   196 SHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSP 260
            |.|||.||||||.||||||||||||||||||||.|||||||||||||||||:|||||||||||||
Mouse   145 SQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSP 209

Human   261 QQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGSSSSLSLRER 325
            |.|||||||||.||||||||||||||..|||||.|||:|||||||.||.||||||:|..|||:||
Mouse   210 QHTLLSMLGIPVLLLASYFLLLTSPEPLDPGGENEAETAARQPLIGTETPESKPGASWDLSLQER 274

Human   326 WTVFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQMLYQAGVFASRSSLRC 390
            |||||||||||:|||:||||||||||||||||||.||||||||||||||||||||||||||||:|
Mouse   275 WTVFKGLLWYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQC 339

Human   391 CRIRFTWALALLQCLNLVFLLADVWFGFLPSIYLVFLIILYEGLLGGAAYVNTFHNIALETSDEH 455
            |||||||.|||||||||..|||||...|||||||:|:||||||||||||||||||||||||||:|
Mouse   340 CRIRFTWVLALLQCLNLALLLADVCLNFLPSIYLIFIIILYEGLLGGAAYVNTFHNIALETSDKH 404

Human   456 REFAMAATCISDTLGISLSGLLALPLHDFLCQL 488
            |||||.|.||||||||||||:||||||||||.|
Mouse   405 REFAMEAACISDTLGISLSGVLALPLHDFLCHL 437

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.