Protein Alignment ADD3 and Add3

DIOPT Version :10

• Sequence 1: NP_058432.1
• Gene: ADD3 / 120
• HGNCID: 245
• Length: 706
• Species: Homo sapiens
• Sequence 2: XP_063137447.1
• Gene: Add3 / 25230
• RGDID: 2043
• Length: 732
• Species: Rattus norvegicus
• Alignment Length: 706
• Identity: 656/706 - (92%)
• Similarity: 688/706 - (97%)
• Gaps: 1/706 - (0%)

Human     1 MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQILQSP 65
            ||||.||.||||||||||||||||||||||:||||:|||||||||||||||||||||||||||||
  Rat    28 MSSDTSQAVITTPPPPSMPHKERYFDRINESDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSP 92

Human    66 AFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPINDLPGADTSSY 130
            ||||||||||||||||||:|||||||||||||||||||:||||||||||||||||||||||||||
  Rat    93 AFREDLECLIQEQMKKGHDPTGLLALQQIADYIMANSFTGFSSPPLSLGMVTPINDLPGADTSSY 157

Human   131 VKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNII 195
            |||||||||||||||||.||||||||||||||||:||||||||||||||||||||||.|||||||
  Rat   158 VKGEKLTRCKLASLYRLADLFGWAHLANTYISVRVSKEQDHIIIIPRGLSFSEATASALVKVNII 222

Human   196 GEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLGDV 260
            |||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||:||||
  Rat   223 GEVVDQGSTNLKIDHSGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDV 287

Human   261 AYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALA 325
            |||||||||:|:||||:|||||||||||||||||||||||||||||||||||||:||||||||:|
  Rat   288 AYYDYQGSLDEEEERIELQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQMACEIQVQAVA 352

Human   326 GAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYR 390
            ||||||||.:||.|||||||:.||.:|||||||||||||||||||||||||||||||||||||||
  Rat   353 GAGGVDNLLILDLQKYKAFTHGVAMTGGGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYR 417

Human   391 HPLIREKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEES 455
            |||:||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||
  Rat   418 HPLVREKPRHKSDVEIPATVTAFSFEDDSVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEES 482

Human   456 RNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAG 520
            ||||||||||||||||||.||||.|||||||||||||||||||.|||||||||||||||||||||
  Rat   483 RNGETSPRTKITWMKAEDPSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAG 547

Human   521 PQSQLLAGIVVDKPPSTMQFEDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEDAEQELLS 585
            ||||||||||||||||||:|||||.||||||||||||.|||||||.:|||||||||:|||||.||
  Rat   548 PQSQLLAGIVVDKPPSTMRFEDDDQGPPAPPNPFSHLMEGELEEYTKTIERKQQGLDDAEQESLS 612

Human   586 DDASSVSQIQSQTQSPQNVPEKLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLS 650
            |||:|||||||||||||:|||:||||||||||||.|::||| :|||||:|||||||||:|||||:
  Rat   613 DDAASVSQIQSQTQSPQSVPERLEENHELFSKSFTSVDVPV-IVNGKDEMHDVEDELAQRVSRLT 676

Human   651 TSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 706
            |||||||||||||||::.||||||:|||||||||||||||||||||||||||||||
  Rat   677 TSTTIENIEITIKSPDRTEEVLSPDGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADD3	NP_058432.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		16/18 (89%)
		Aldolase_II	137..385	CDD:469663	230/247 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	471..497		23/25 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	535..555		17/19 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	575..610		29/34 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	666..706		35/39 (90%)
		Interaction with calmodulin. /evidence=ECO:0000255	684..701		16/16 (100%)
Add3	XP_063137447.1	None