Protein Alignment ADD3 and add-1

DIOPT Version :10

• Sequence 1: NP_058432.1
• Gene: ADD3 / 120
• HGNCID: 245
• Length: 706
• Species: Homo sapiens
• Sequence 2: NP_001024640.1
• Gene: add-1 / 180760
• WormBaseID: WBGene00000072
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 267
• Identity: 52/267 - (19%)
• Similarity: 99/267 - (37%)
• Gaps: 87/267 - (32%)

Human   849 IGWIISNSPELFSGMLK------IRIGWIIHAMEYELQVRGGDKPAVDLYQLS------------ 895
            :||..||. .:|||:..      ..|..|:..:   |..:||....:.::.|.
 Worm     1 MGWRCSNI-MVFSGLFSASSTTDFTIREIVRCL---LLAKGGIDAVLLVFSLRNRLTEEEQSTLR 61

Human   896 ------PSEVKQLLLDILQPQQSGRCWLNRRQIDGSLNRTPPEFYDRVWQILERTPNGIVVAGKH 954
                  .|::...::.:...:.:..|   ...:|..|... |||.    :|||...:..|
 Worm    62 TLKILFGSQIVDYIIVVFTNEDALEC---GETLDDYLEDC-PEFQ----EILEECDDRKV----- 113

Human   955 LPQQPTLSDMTMYEMNFSLLVEDMLGNIDQPKYRQIIVELLMVVSIVLERNPELEFQDKVDLDRL 1019
                       :::.:::..|        ..|.|| :.:||.:|..:.::|....:.  .||.
 Worm   114 -----------LFDNSYNAPV--------SKKDRQ-VHDLLNLVEQISKKNNGKSYM--ADLS-- 154

Human  1020 VKEAFHEFQKDESRLKEIEKQ-DDMTSFYNTPPLGKRGTCSYLTKVV---MNSLLEG-------E 1073
                 ||.:::|:.:||.:|| ::|..:      ..:...|.:.|.:   .|.:|||       :
 Worm   155 -----HELRENEATIKEKQKQIEEMKGW------SSKQEISQMKKELEKSHNEMLEGIKEKISNQ 208

Human  1074 VKPSNED 1080
            :|.|.||
 Worm   209 LKESLED 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADD3	NP_058432.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Aldolase_II	137..385	CDD:469663
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	471..497
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	535..555
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	575..610
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	666..706
		Interaction with calmodulin. /evidence=ECO:0000255	684..701
add-1	NP_001024640.1	Aldolase_II	115..360	CDD:469663	28/125 (22%)