DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hnrnpd and Rb97D

DIOPT Version :9

Sequence 1:	NP_001070733.1	Gene:	Hnrnpd / 11991	MGIID:	101947	Length:	355	Species:	Mus musculus
Sequence 2:	NP_001014671.1	Gene:	Rb97D / 43231	FlyBaseID:	FBgn0004903	Length:	471	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	100/317 - (31%)
Similarity:	148/317 - (46%)	Gaps:	74/317 - (23%)

- Green bases have known domain annotations that are detailed below.

Mouse    84 PRHTEAA----AAQREE---------WKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITG 135
            |...|:|    .|.|||         .|:|||||:..||:::||.::.::|:|||..:..|..|.
  Fly     6 PLSDESADVIVLADREEDDICELEHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATK 70

Mouse   136 RSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRA------KAMKTKEPVKKIFVGGLSPDTP 194
            |||||||:.:.:|..||:..:.:.|.::||.::.|||      ::.:|...|||:|||||..:..
  Fly    71 RSRGFGFITYTKSLMVDRAQENRPHIIDGKTVEAKRALPRPERESRETNISVKKLFVGGLKDNHD 135

Mouse   195 EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMS 259
            ||.:||||..||.|.|::|..|..|.|||||.|:.|.:.:.|.|.:.||.|.:.....::|.::.
  Fly   136 EECLREYFLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHAIKYVHVDVKKSIY 200

Mouse   260 KEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYN--------------SQ 310
            ....:::||   .||.|...:     ||.|..|     ..||.|....|              .|
  Fly   201 NLDKKEKQQ---PGGLANAIK-----PSLNQQQ-----QQQGGGQQPPNGNMQAPSFRPPVPPQQ 252

Mouse   311 GYGGY-------------GGYDYTG-----YNNYY---------GYGDY-SNQQSGY 339
            ..|.|             ..::|.|     ...||         |:|.| ..||:|:
  Fly   253 AMGPYQQQPPPAPMSAPPPNFNYWGPPPPAMPPYYQQPPPQQMNGWGPYPPPQQNGW 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hnrnpd	NP_001070733.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91		3/10 (30%)
		CBFNT	<60..78	CDD:311868
		RRM1_hnRNPD_like	99..172	CDD:241019	29/72 (40%)
		RRM2_hnRNPD	183..257	CDD:241027	32/73 (44%)
Rb97D	NP_001014671.1	RRM1_hnRNPA_like	33..110	CDD:241022	32/76 (42%)
Rb97D	NP_001014671.1	RRM2_hnRNPA_like	124..196	CDD:240774	31/71 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910