Protein Alignment CLK3 and clk4a

DIOPT Version :9

• Sequence 1: NP_001123500.2
• Gene: CLK3 / 1198
• HGNCID: 2071
• Length: 490
• Species: Homo sapiens
• Sequence 2: XP_003199888.1
• Gene: clk4a / 321857
• ZFINID: ZDB-GENE-030131-576
• Length: 496
• Species: Danio rerio
• Alignment Length: 510
• Identity: 247/510 - (48%)
• Similarity: 335/510 - (65%)
• Gaps: 44/510 - (8%)

Human     1 MHHCKRYRSP------EPDPYLSYRWKRRR-SYSREHEGRLR---YPSRREPPPRRSRSRSHDRL 55
            |...:|.|||      ..|..:..|.:.|| |:|.|.|.:.|   :..:........:..|::||
Zfish     1 MRQTQRERSPWLRELSLEDRIMETRKRHRRDSHSSERENKYRKHHHHYKNSDGHCLEKRSSNERL 65

Human    56 PYQRRYRERRD---------SDTYRCEERSPSFGEDYYGPSRSRHRRRSRER----------GPY 101
            ....::...||         .|..|..:||         .||.|||.|.|:|          ...
Zfish    66 DTSEKHAVFRDHEHNGYAACKDKERNRDRS---------RSRERHRERERDRDWHHYSKSSGNSM 121

Human   102 RTRKHAH-HCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEG 165
            |:.:|.| |.|:|     |...|.|:...::.|||||||:|||||...||.|:.|||||..||||
Zfish   122 RSSRHRHRHRHRR-----SHPHSDSRSHRRKRSRSVEDDEEGHLVYHSGDMLRARYEIVCTLGEG 181

Human   166 TFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHG 230
            .|||||||:||.:..:::|||||:|:.:||:||..|:.||::|...|.:.::.||.|.|||:.||
Zfish   182 AFGKVVECIDHEKVGARIALKIIKNIERYRDAALSEVEVLEQINSLDCDRRYACVRMYDWFDHHG 246

Human   231 HMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSE 295
            |:||||||||.:|::|||||||||:.:.|:||||||:..|:||||:|:|||||||||||||||||
Zfish   247 HICIAFELLGLSTYDFLKENNFQPFYINHIRHMAYQIIRAVRFLHKNKLTHTDLKPENILFVNSE 311

Human   296 FETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI 360
            :...||.....:|::|||..::|.|||:||::|||||::|:|||||.|||||:|||:..|||||:
Zfish   312 YNIRYNSKMKRDERTVKNPDVKVVDFGNATYEHEHHTSVVSTRHYRAPEVILDLGWSHSCDVWSV 376

Human   361 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVK 425
            ||||.|||.|.||||||:::|||.|||::|||||:||:.:|||.::.....|.||.:||.||||:
Zfish   377 GCILIEYYLGSTLFQTHDSKEHLAMMERVLGPIPTHMLQKTRKSRFVRNDKLDWDIHSSSGRYVR 441

Human   426 ENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER 480
            :.||||:.|::..|.:|.|||||:.||||:|..:||||.||:.||||..:...::
Zfish   442 KQCKPLRQYLVSSSSDHEQLFDLIERMLEYDVTKRITLDEAIKHPFFNSIRKSKK 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLK3	NP_001123500.2	PKc_CLK3	142..472	CDD:271116	197/329 (60%)
clk4a	XP_003199888.1	PKc_like	159..488	CDD:304357	196/328 (60%)
		S_TKc	172..488	CDD:214567	189/315 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194336399
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D160563at33208
OrthoFinder	1	1.000	-	-		FOG0000672
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100708
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X440
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.650