Protein Alignment CLK2 and Hipk

DIOPT Version :9

• Sequence 1: NP_001281267.1
• Gene: CLK2 / 1196
• HGNCID: 2069
• Length: 499
• Species: Homo sapiens
• Sequence 2: NP_001369036.1
• Gene: Hipk / 38070
• FlyBaseID: FBgn0035142
• Length: 1409
• Species: Drosophila melanogaster
• Alignment Length: 387
• Identity: 118/387 - (30%)
• Similarity: 192/387 - (49%)
• Gaps: 66/387 - (17%)

Human   131 SSSQHSSRRAKSVEDDAEGHLIYH-VGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGAR-VALK 193
            :::|..|:|:.| ..|.:..|:.| |...|...||::..||.||||:||:|  .:||.:. ||:|
  Fly   160 ANTQPPSKRSSS-GADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKC--WKRGTSEIVAIK 221

Human   194 IIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNN 258
            |:||...|....::|:::|.::::::.|..|. |:.|:.|.:..|.|:.||:|..:.:||||.|.
  Fly   222 ILKNHPSYARQGQIEVSILSRLSQENADEFNF-VRAFECFQHKNHTCLVFEMLEQNLYDFLKQNK 285

Human   259 YLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVN---SDYELTYNLEKKRDERSVKS 320
            :.|.|:..:|.:..|:..|:..|....|.|.|||||||:.|:   ..|.
  Fly   286 FSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYR---------------- 334

Human   321 TAVRVVDFGSATFDHEHHS-----TIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTL 380
              |:|:|||||:    |.|     |.:.:|:|||||:||.|.:.:..|:||:||::.|.::|:.|
  Fly   335 --VKVIDFGSAS----HVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLGWPL 393

Human   381 FQTHDNREHLAMMERILGPIPSRMIRKTRK-QKYFYRGRLD-----WDENTSAGRYVREN--CKP 437
            :......:.:..:.:..|.....|:....| .|:|||. :|     |...|:.......|  .|.
  Fly   394 YPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRD-VDSTYPFWRLKTTEEHEAETNTKSKE 457

Human   438 LRRY---------------------LTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPF 478
            .|:|                     |.:|..:..:..||::.||..:..:|||..|||.|.|
  Fly   458 ARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSF 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLK2	NP_001281267.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..67
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..143		3/11 (27%)
		PKc_CLK2	150..479	CDD:271117	113/368 (31%)
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	109/354 (31%)
		PHA03378	<1080..1327	CDD:223065

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810