Protein Alignment GSTO2 and GstE6

DIOPT Version :10

• Sequence 1: NP_899062.1
• Gene: GSTO2 / 119391
• HGNCID: 23064
• Length: 243
• Species: Homo sapiens
• Sequence 2: NP_611328.1
• Gene: GstE6 / 37111
• FlyBaseID: FBgn0063494
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 219
• Identity: 44/219 - (20%)
• Similarity: 81/219 - (36%)
• Gaps: 57/219 - (26%)

Human    24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL----RNKPEWYYTKHPFGHIPVLETSQCQLIY 84
            :.:|.:...|.....:|.|.|.::.:|.||:::    :..|| |..|:|...:|.|| .....|:
  Fly     4 LTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPE-YLEKNPQHTVPTLE-DDGHYIW 66

Human    85 ESVIACEYLDDAY-PGRKLFPYDPYERA---------------------RQKMLLELFCKVPHLT 127
            :|.....||...| ....|:|.||.:||                     .:.:|.:...|||
  Fly    67 DSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVP--- 128

Human   128 KECLVALRCGRECTNLKAALRQEFSNLEEILEYQNT-----TFFGGTCISMIDYLLWPWFERLDV 187
                                ::.:..:.||.::..|     .:..|..:::.|:.|......|:.
  Fly   129 --------------------KERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEA 173

Human   188 YGILDCVSHTPALRLWISAMKWDP 211
            :..||...: |.:..||..::..|
  Fly   174 FVALDTTKY-PRIGAWIKKLEQLP 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTO2	NP_899062.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	7..94	CDD:469754	19/73 (26%)
		GST_C_Omega	108..230	CDD:198293	19/130 (15%)
GstE6	NP_611328.1	GstA	4..201	CDD:440390	44/219 (20%)