Protein Alignment GSTO2 and GstE1

DIOPT Version :10

• Sequence 1: NP_899062.1
• Gene: GSTO2 / 119391
• HGNCID: 23064
• Length: 243
• Species: Homo sapiens
• Sequence 2: NP_611323.1
• Gene: GstE1 / 37106
• FlyBaseID: FBgn0034335
• Length: 224
• Species: Drosophila melanogaster
• Alignment Length: 220
• Identity: 44/220 - (20%)
• Similarity: 90/220 - (40%)
• Gaps: 41/220 - (18%)

Human    24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR---NKPEWYYTKHPFGHIPVLETSQCQLIYE 85
            |.:|.....|.....:|.||..::.:|...:||:   :..|.|..|:|...:|:|:.:. ..|::
  Fly     6 IVLYGTDLSPCVRTVKLTLKVLNLDYEYKEVNLQAGEHLSEEYVKKNPQHTVPMLDDNG-TFIWD 69

Human    86 SVIACEYLDDAY-PGRKLFPYDPYERA--RQKMLLE---LFCKVPHLTKECLV--ALRCGRECTN 142
            |.....||.|.| ...:|:|.|..:||  .|::..:   ::..:.::::...:  .....:|..:
  Fly    70 SHAIAAYLVDKYAKSDELYPKDLAKRAIVNQRLFFDASVIYASIANVSRPFWINGVTEVPQEKLD 134

Human   143 LKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP---------------------WFERLD 186
               |:.|....||..|  .|:.:..|..:::.|....|                     |.:||:
  Fly   135 ---AVHQGLKLLETFL--GNSPYLAGDSLTLADLSTGPTVSAVPAAVDIDPATYPKVTAWLDRLN 194

Human   187 VYGILDCVSHTPALRLWISAM--KW 209
            .......::..|| :.:::.:  ||
  Fly   195 KLPYYKEINEAPA-QSYVAFLRSKW 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTO2	NP_899062.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	7..94	CDD:469754	18/72 (25%)
		GST_C_Omega	108..230	CDD:198293	20/132 (15%)
GstE1	NP_611323.1	GstA	6..201	CDD:440390	40/200 (20%)