DRSC/TRiP Functional Genomics Resources

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Protein Alignment CLIC2 and GstE6

DIOPT Version :10

Sequence 1:NP_001280.3 Gene:CLIC2 / 1193 HGNCID:2063 Length:247 Species:Homo sapiens
Sequence 2:NP_611328.1 Gene:GstE6 / 37111 FlyBaseID:FBgn0063494 Length:222 Species:Drosophila melanogaster


Alignment Length:15 Identity:8/15 - (53%)
Similarity:13/15 - (86%) Gaps:0/15 - (0%)


- Green bases have known domain annotations that are detailed below.


Human   173 FLDGDQLTLADCSLL 187
            ::.|:|||:||.||:
  Fly   151 YIAGNQLTIADFSLV 165

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CLIC2NP_001280.3 Required for insertion into the membrane. /evidence=ECO:0000250 1..96
N-terminal 1..94
O-ClC 12..245 CDD:129941 8/15 (53%)
G-site. /evidence=ECO:0000305|PubMed:25581026 30..33
Joint loop 95..106
C-terminal 107..247 8/15 (53%)
Foot loop 151..171
GstE6NP_611328.1 GstA 4..201 CDD:440390 8/15 (53%)
Blue background indicates that the domain is not in the aligned region.

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