DRSC/TRiP Functional Genomics Resources

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Protein Alignment CLIC2 and GstE5

DIOPT Version :10

Sequence 1:NP_001280.3 Gene:CLIC2 / 1193 HGNCID:2063 Length:247 Species:Homo sapiens
Sequence 2:NP_611327.1 Gene:GstE5 / 37110 FlyBaseID:FBgn0063495 Length:222 Species:Drosophila melanogaster


Alignment Length:32 Identity:11/32 - (34%)
Similarity:19/32 - (59%) Gaps:4/32 - (12%)


- Green bases have known domain annotations that are detailed below.


Human   173 FLDGDQLTLADCSLLPKLN----IIKVAAKKY 200
            ::.|||||:||.||:..:.    .:::...||
  Fly   151 YIAGDQLTIADFSLISSITSLVAFVEIDRLKY 182

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CLIC2NP_001280.3 Required for insertion into the membrane. /evidence=ECO:0000250 1..96
N-terminal 1..94
O-ClC 12..245 CDD:129941 11/32 (34%)
G-site. /evidence=ECO:0000305|PubMed:25581026 30..33
Joint loop 95..106
C-terminal 107..247 11/32 (34%)
Foot loop 151..171
GstE5NP_611327.1 GstA 4..210 CDD:440390 11/32 (34%)
Blue background indicates that the domain is not in the aligned region.

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