Protein Alignment CLIC2 and GstE4

DIOPT Version :10

• Sequence 1: NP_001280.3
• Gene: CLIC2 / 1193
• HGNCID: 2063
• Length: 247
• Species: Homo sapiens
• Sequence 2: NP_611326.1
• Gene: GstE4 / 37109
• FlyBaseID: FBgn0063496
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 69
• Identity: 20/69 - (28%)
• Similarity: 34/69 - (49%)
• Gaps: 19/69 - (27%)

Human   148 DYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGV 212
            |::.| .||:.|             |:.|||||:||.|::..:..|.|    :.:.| ||::..:
  Fly   140 DFVET-FLDDHD-------------FVAGDQLTIADFSIVSTITSIGV----FLELD-PAKYPKI 185

Human   213 WRYL 216
            ..:|
  Fly   186 AAWL 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLIC2	NP_001280.3	Required for insertion into the membrane. /evidence=ECO:0000250	1..96
		N-terminal	1..94
		O-ClC	12..245	CDD:129941	20/69 (29%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	30..33
		Joint loop	95..106
		C-terminal	107..247		20/69 (29%)
		Foot loop	151..171		4/19 (21%)
GstE4	NP_611326.1	GstA	6..209	CDD:440390	20/69 (29%)