DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Neurod4 and amos

DIOPT Version :9

Sequence 1:	NP_001316418.1	Gene:	Neurod4 / 11923	MGIID:	108055	Length:	330	Species:	Mus musculus
Sequence 2:	NP_477446.1	Gene:	amos / 35110	FlyBaseID:	FBgn0003270	Length:	198	Species:	Drosophila melanogaster

Alignment Length:	155	Identity:	49/155 - (31%)
Similarity:	68/155 - (43%)	Gaps:	31/155 - (20%)

- Green bases have known domain annotations that are detailed below.

Mouse     3 KMYMKSKDMVEL---VNTQSWM-----------DKGLSSQNEMKEQERRPGSYGMLGTLTEEHDS 53
            :||..:..::||   :|.|...           ::|.|.:...|:|..:|  |..|.|......|
  Fly    57 EMYYDTPSVLELEHMLNAQEQQQHHLQANPLGKNQGRSPRYWNKQQRSKP--YDKLSTSMSSSTS 119

Mouse    54 IEEDEEEEEDGDKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYS 118
            ..........|    ..|...||           ||:.||||||.||:.||||.|.||.|:|...
  Fly   120 SASSSSSSSAG----FGGEVLKK-----------RRLAANARERRRMNSLNDAFDKLRDVVPSLG 169

Mouse   119 KTQKLSKIETLRLARNYIWALSEVL 143
            ..::|||.|||::|:.||..|..:|
  Fly   170 HDRRLSKYETLQMAQAYIGDLVTLL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Neurod4	NP_001316418.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..80		13/56 (23%)
		HLH	88..144	CDD:238036	30/56 (54%)
		Neuro_bHLH	146..263	CDD:289310
amos	NP_477446.1	HLH	137..195	CDD:238036	32/69 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2611
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.870