DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Atoh1 and tap

DIOPT Version :9

Sequence 1:NP_031526.1 Gene:Atoh1 / 11921 MGIID:104654 Length:351 Species:Mus musculus
Sequence 2:NP_524124.1 Gene:tap / 39935 FlyBaseID:FBgn0015550 Length:398 Species:Drosophila melanogaster


Alignment Length:347 Identity:83/347 - (23%)
Similarity:125/347 - (36%) Gaps:96/347 - (27%)


- Green bases have known domain annotations that are detailed below.


Mouse    30 PLTPQP--PATLQARDLPVYPAE-LSLLDSTDPRAWLT-PTLQGLCTARAAQYLLHSPELGASEA 90
            |..|||  ..|..|..|...||. :.|||::...:..: .||.....:||...:. .|.|.::..
  Fly    54 PAIPQPYSGGTWDAVPLSSPPAGFVGLLDTSSNHSTRSGRTLVEHLNSRATNGVF-DPPLTSTPV 117

Mouse    91 AAPRDEADSQGELVRRSGCGGLSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQK 155
            .:|.|                 ..:|.|          |....|.:...:|.|:|:  ||..:::
  Fly   118 KSPED-----------------PNAPRP----------KRKYAVGKNRVTRSRSPT--QVVKIKR 153

Mouse   156 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPN---- 216
            .||:.||.|||.|||.||.|.::||..:||...:.||:|.|.|:.|..||.||.::|::..    
  Fly   154 FRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKLTKIEILRFAHNYIFALEQVLESGGSINL 218

Mouse   217 ------------------------VGEQPPPPTASCKNDHHHLRTASSYEGGAGASAVAGAQPAP 257
                                    |..||.|            .....:..|.|.:.:|..|.||
  Fly   219 DLEKLQNFTLSGERITKELFDALFVNPQPYP------------LFGRMFPYGQGMAPLAQHQTAP 271

Mouse   258 GGGPRPTPPGPCRTRFSGPASSGGYSVQLD-ALHFPAFEDRALTAMMAQKDLSPSLPGGILQPVQ 321
            .            :....|.:.||:...:| ....|.|:.........|:...|..|.. |||  
  Fly   272 A------------SHAEQPPAMGGFQHGMDYPQQPPGFDFTGSMRFYHQQQQQPHQPHH-LQP-- 321

Mouse   322 EDNSKTSPRSHRSDGEFSPHSH 343
                  :|:...|..:||...:
  Fly   322 ------NPQQESSPQQFSQEKY 337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atoh1NP_031526.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..39 4/10 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 89..116 2/26 (8%)
HLH 155..213 CDD:238036 27/57 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 244..278 7/33 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 308..351 9/36 (25%)
tapNP_524124.1 HLH 155..207 CDD:278439 26/51 (51%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167835501
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

Return to query results.
Submit another query.