DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atoh1 and twi

DIOPT Version :9

Sequence 1:NP_031526.1 Gene:Atoh1 / 11921 MGIID:104654 Length:351 Species:Mus musculus
Sequence 2:NP_001033967.1 Gene:twi / 37655 FlyBaseID:FBgn0003900 Length:490 Species:Drosophila melanogaster


Alignment Length:227 Identity:63/227 - (27%)
Similarity:92/227 - (40%) Gaps:49/227 - (21%)


- Green bases have known domain annotations that are detailed below.


Mouse    77 QYLLHSPELGASE----AAAPRDEAD--SQGELVRRSGCGGLSKSPGPVKVREQLCKLKGGVVVD 135
            :|..|:.....|:    ..:|...||  |.|.|:..|..||.:..    |.|.:|          
  Fly   297 EYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFR----KPRRRL---------- 347

Mouse   136 ELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQM 200
                  :|.||..:.......:|:.||.|||:|...||.||..|:.:||:..:| ||||.:||::
  Fly   348 ------KRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKL 405

Mouse   201 AQIYINALSELLQTPNVG-----EQPPPPTASCKNDHHHLRTASSYEGGA--GASAVAGAQPAPG 258
            |..||:.|..:|.:.::.     |....|:|        ..:|||....|  ||.|.........
  Fly   406 ATRYIDFLCRMLSSSDISLLKALEAQGSPSA--------YGSASSLLSAAANGAEADLKCLRKAN 462

Mouse   259 GGPRPTPPGPCRTRFSGPASSGGYSVQLDALH 290
            |.| ..||......|      |.:.::.||.|
  Fly   463 GAP-IIPPEKLSYLF------GVWRMEGDAQH 487

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atoh1NP_031526.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..39
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 89..116 9/32 (28%)
HLH 155..213 CDD:238036 25/57 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 244..278 9/35 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 308..351
twiNP_001033967.1 HLH 363..413 CDD:278439 24/50 (48%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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