DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atoh1 and sc

DIOPT Version :10

Sequence 1:NP_031526.1 Gene:Atoh1 / 11921 MGIID:104654 Length:351 Species:Mus musculus
Sequence 2:NP_476803.1 Gene:sc / 30982 FlyBaseID:FBgn0004170 Length:345 Species:Drosophila melanogaster


Alignment Length:273 Identity:68/273 - (24%)
Similarity:97/273 - (35%) Gaps:81/273 - (29%)


- Green bases have known domain annotations that are detailed below.


Mouse   110 GGLSKSPG---PVKVREQLCKLKGGVVVDELGCSRQ-------RAPSSKQVNGVQK-QRRLAANA 163
            ||....|.   |:|.|:...:   |:.:..  ||..       .:|:...|:..|. |||   ||
  Fly    50 GGNQNQPAGTMPIKTRKYTPR---GMALTR--CSESVSSLSPGSSPAPYNVDQSQSVQRR---NA 106

Mouse   164 RERRRMHGLNHAFDQLRNVIP-SFNND----------KKLSKYETLQMAQIYINALSELLQTPNV 217
            |||.|:..:|::|.:||..|| |...|          ||:||.:||::|..||..|.:|:...|.
  Fly   107 RERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNG 171

Mouse   218 GEQPPPPTASCKNDHHHLRTASSYEGGAGASAVAGAQPAPGGGPRPTPPGPCRTRFSGPASSGGY 282
            |.     .....|....|:..........:|                         |...||.|:
  Fly   172 GS-----NIGANNAVTQLQLCLDESSSHSSS-------------------------SSTCSSSGH 206

Mouse   283 SV------------QLDALHFPAFEDRALTAMMAQKDL-SPSLPGGILQPVQEDNSKTSPRSHRS 334
            :.            |...|....|..:.|||:....:| ..|:|||....|  ..||.....|  
  Fly   207 NTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCV--STSKNQQTCH-- 267

Mouse   335 DGEFSPHSHYSDS 347
                ||.|.::.|
  Fly   268 ----SPTSSFNSS 276

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atoh1NP_031526.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..39
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 89..116 2/5 (40%)
bHLH_TS_ATOH1 152..215 CDD:381556 29/74 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 244..278 2/33 (6%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 308..351 13/41 (32%)
scNP_476803.1 bHLH_TS_dAS-C_like 100..166 CDD:381587 27/68 (40%)
Blue background indicates that the domain is not in the aligned region.

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