Protein Alignment CLIC1 and GstD8

DIOPT Version :10

• Sequence 1: NP_001279.2
• Gene: CLIC1 / 1192
• HGNCID: 2062
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_524916.1
• Gene: GstD8 / 48341
• FlyBaseID: FBgn0010044
• Length: 212
• Species: Drosophila melanogaster
• Alignment Length: 133
• Identity: 31/133 - (23%)
• Similarity: 54/133 - (40%)
• Gaps: 52/133 - (39%)

Human    81 EEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLT 145
            :.|:||:     ||:                      |:|::||..:.::| :..|...||.:|
  Fly   106 QSFVEAI-----YPQ----------------------IRNNHPADPEAMQK-VDSAFGHLDTFL- 141

Human   146 SPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYL 210
                        ||:     :::.|:.||:||..||..:...:||     .|.|.: :..|.|:.
  Fly   142 ------------EDQ-----EYVAGDCLTIADIALLASVSTFEVV-----DFDIAQ-YPNVARWY 183

Human   211 SNA 213
            .||
  Fly   184 ENA 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90		3/8 (38%)
		O-ClC	6..241	CDD:129941	31/133 (23%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	24..27
GstD8	NP_524916.1	GST_N_Delta_Epsilon	1..74	CDD:239343
		GST_C_Delta_Epsilon	88..204	CDD:198287	31/133 (23%)