Protein Alignment CLIC1 and GstD7

DIOPT Version :10

• Sequence 1: NP_001279.2
• Gene: CLIC1 / 1192
• HGNCID: 2062
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_525114.1
• Gene: GstD7 / 48340
• FlyBaseID: FBgn0010043
• Length: 224
• Species: Drosophila melanogaster
• Alignment Length: 204
• Identity: 47/204 - (23%)
• Similarity: 81/204 - (39%)
• Gaps: 41/204 - (20%)

Human    25 PFSQRLFMVLWLKGVTFNVTTVDT----KRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFL- 84
            |.|:.:.||....|:..|...::|    :.:.|.| ::.|...:|.|:....|..::..|..:|
  Fly    13 PASRAIQMVAKALGLELNSKLINTMEGDQLKPEFV-RINPQHTIPTLVDNGFVIWESRAIAVYLV 76

Human    85 EAVLCP--PRYP----KLAALNP----ESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKV 139
            |....|  |.||    |.|.:|.    :..|. .|...|:...|..:....:......:..|...
  Fly    77 EKYGKPDSPLYPNDPQKRALINQRLYFDMGTL-YDALTKYFFLIFRTGKFGDQEALDKVNSAFGF 140

Human   140 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFR 204
            |:.:|               ||   :.|:.|::||:||..:|..:..|:     :..|.:.: |.
  Fly   141 LNTFL---------------EG---QDFVAGSQLTVADIVILATVSTVE-----WFSFDLSK-FP 181

Human   205 GVHRYLSNA 213
            .|.|:|.||
  Fly   182 NVERWLKNA 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90		16/69 (23%)
		O-ClC	6..241	CDD:129941	47/204 (23%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	24..27		1/1 (100%)
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	15/64 (23%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	27/124 (22%)