DRSC/TRiP Functional Genomics Resources

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Protein Alignment CLIC1 and GstD9

DIOPT Version :10

Sequence 1:NP_001279.2 Gene:CLIC1 / 1192 HGNCID:2062 Length:241 Species:Homo sapiens
Sequence 2:NP_650181.1 Gene:GstD9 / 41502 FlyBaseID:FBgn0038020 Length:218 Species:Drosophila melanogaster


Alignment Length:137 Identity:29/137 - (21%)
Similarity:50/137 - (36%) Gaps:38/137 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    92 RYPKLAALNPE--------SNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPL 148
            :|.|..:|.|:        :.....|:...:.:|:....|.|.::::|                 
  Fly    76 KYDKDGSLYPKDPQQRAVINQRLFFDLSTLYQSYVYYYYPQLFEDVKK----------------- 123

Human   149 PEEVDETSAEDEGVSQ-RKFLDG------NELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGV 206
            |.:.|.....|:..:. ...|.|      |:|||||..||..:...::  .:|.....||    |
  Fly   124 PADPDNLKKIDDAFAMFNTLLKGQQYAALNKLTLADFALLATVSTFEI--SEYDFGKYPE----V 182

Human   207 HRYLSNA 213
            .|:..||
  Fly   183 VRWYDNA 189

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CLIC1NP_001279.2 Required for insertion into the membrane 2..90
O-ClC 6..241 CDD:129941 29/137 (21%)
G-site. /evidence=ECO:0000305|PubMed:25581026 24..27
GstD9NP_650181.1 GstA 1..187 CDD:440390 27/133 (20%)
Blue background indicates that the domain is not in the aligned region.

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