DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment CLIC1 and GstE6

DIOPT Version :10

Sequence 1:	NP_001279.2	Gene:	CLIC1 / 1192	HGNCID:	2062	Length:	241	Species:	Homo sapiens
Sequence 2:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	15	Identity:	7/15 - (46%)
Similarity:	13/15 - (86%)	Gaps:	0/15 - (0%)

- Green bases have known domain annotations that are detailed below.

Human   167 FLDGNELTLADCNLL 181
            ::.||:||:||.:|:
  Fly   151 YIAGNQLTIADFSLV 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90
		O-ClC	6..241	CDD:129941	7/15 (47%)
		G-site. /evidence=ECO:0000305\|PubMed:25581026	24..27
GstE6	NP_611328.1	GstA	4..201	CDD:440390	7/15 (47%)
Blue background indicates that the domain is not in the aligned region.

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