DRSC/TRiP Functional Genomics Resources

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Protein Alignment CLIC1 and GstE4

DIOPT Version :10

Sequence 1:NP_001279.2 Gene:CLIC1 / 1192 HGNCID:2062 Length:241 Species:Homo sapiens
Sequence 2:NP_611326.1 Gene:GstE4 / 37109 FlyBaseID:FBgn0063496 Length:222 Species:Drosophila melanogaster


Alignment Length:59 Identity:20/59 - (33%)
Similarity:28/59 - (47%) Gaps:15/59 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    73 VHTDTNKIEEFLEAVLCPPRYPKLAA---------LNPESNTAGLDIFAKFSAYIKNSN 122
            |.|.|: |..|||  |.|.:|||:||         ...|:|..|.   |:|...:::.|
  Fly   165 VSTITS-IGVFLE--LDPAKYPKIAAWLERLKELPYYEEANGKGA---AQFVELLRSKN 217

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CLIC1NP_001279.2 Required for insertion into the membrane 2..90 8/16 (50%)
O-ClC 6..241 CDD:129941 20/59 (34%)
G-site. /evidence=ECO:0000305|PubMed:25581026 24..27
GstE4NP_611326.1 GstA 6..209 CDD:440390 18/49 (37%)
Blue background indicates that the domain is not in the aligned region.

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