Protein Alignment CLIC1 and GstT1

DIOPT Version :10

• Sequence 1: NP_001279.2
• Gene: CLIC1 / 1192
• HGNCID: 2062
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_610509.2
• Gene: GstT1 / 35995
• FlyBaseID: FBgn0050000
• Length: 228
• Species: Drosophila melanogaster
• Alignment Length: 192
• Identity: 44/192 - (22%)
• Similarity: 69/192 - (35%)
• Gaps: 55/192 - (28%)

Human     5 QPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLY 69
            ||...|::     ..|:|..||......:...:.:|      |..|.....||      :|.::.
  Fly    14 QPSRALWI-----AMKLGKTPFEDCPVALRKQEQLT------DEYRSINRFQK------VPAIVD 61

Human    70 GTEVHTDTNKIEEFL--EAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNL--- 129
            |.....::..|..:|  :.|.....|||..     ...|.:|.|.::..:    |..|..:|
  Fly    62 GKFQLGESVSIVRYLADKGVFSEQLYPKTL-----EERARVDEFLEWQHF----NVRLVCSLFFR 117

Human   130 ------EKGLLKALKVLDNYLTSPLPEEVDETSAEDE---GVSQR-----KFLDGNELTLAD 177
                  .|||..|          |.||.|.:...:.|   |:.:|     .||.|::||:||
  Fly   118 QVWLLPAKGLAPA----------PKPESVKKLIKDVESNLGLLERLWLEKDFLVGDKLTVAD 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90		17/86 (20%)
		O-ClC	6..241	CDD:129941	43/191 (23%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	24..27		1/2 (50%)
GstT1	NP_610509.2	GST_N_Theta	5..80	CDD:239348	16/82 (20%)
		GST_C_Theta	93..218	CDD:198292	24/91 (26%)