Protein Alignment CLIC1 and GstT3

DIOPT Version :10

• Sequence 1: NP_001279.2
• Gene: CLIC1 / 1192
• HGNCID: 2062
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_001162808.1
• Gene: GstT3 / 33047
• FlyBaseID: FBgn0031117
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 37/193 - (19%)
• Similarity: 60/193 - (31%)
• Gaps: 80/193 - (41%)

Human    27 SQRLFMVLWLKGVTFNVTTV----------DTKRRTETVQK--------------------LCPG 61
            |:.||::..|..:.|....|          |.|:.....|:                    |...
  Fly    56 SRALFIIFRLSNMPFEDCVVALRNGEHLTEDFKKEINRFQRVPCIHDNGYKLAESVAILRYLSAK 120

Human    62 GQLPFLLYGTEVHTDTNKIEEFLE------AVLCPPRY------PKLAALNPESNTAGLDIFAKF 114
            |::|..|| .:...|.::::||||      .:.|...:      |.|....|.
  Fly   121 GKIPEHLY-PKYFVDQSRVDEFLEWQHMSLRLTCAMYFRTVWLEPLLTGRTPS------------ 172

Human   115 SAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLAD 177
            .|.|:.....:..||:                 :.|||        .:..:.||.|:.||:||
  Fly   173 EAKIETFRMQMERNLD-----------------VVEEV--------WLEGKDFLTGSSLTVAD 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90		19/98 (19%)
		O-ClC	6..241	CDD:129941	37/193 (19%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	24..27		37/193 (19%)
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	10/64 (16%)
		GST_C_Theta	135..259	CDD:198292	22/113 (19%)