DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atf3 and Atf3

DIOPT Version :9

Sequence 1:	NP_031524.2	Gene:	Atf3 / 11910	MGIID:	109384	Length:	181	Species:	Mus musculus
Sequence 2:	NP_001259125.1	Gene:	Atf3 / 43867	FlyBaseID:	FBgn0028550	Length:	688	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	66/194 - (34%)
Similarity:	93/194 - (47%)	Gaps:	56/194 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse     5 HPGQVSASEVSATAIV---PCLSPPGSLVFEDFANLTP--------FVKEELRFAIQNK------ 52
            ||...|.|:.|:.:..   |..||.|:..       ||        .:||.|:.:||:|
  Fly    82 HPNGQSHSQDSSHSSCSGSPLDSPAGTAT-------TPSVQQTCSRLIKEGLKLSIQSKRKLSTC 139

Mouse    53 -------------------HLCHRMSSALESVTVNN----------RPLEMSVTKSE---AAPEE 85
                               |..|..||...|.:::|          ...:.|.|||:   ..||:
  Fly   140 DSSSGSEQPHSKYSRRSSNHNGHSGSSNNYSGSMSNANDLDDDCEESSDDDSETKSQPKGLTPED 204

Mouse    86 DERKRRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLH 149
            ::|:|||||||||||.|||.||:|:|:.|.||||.|::.|.|||.|:.:|:.|:|.|:.||..|
  Fly   205 EDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVELKNQVRQLETERQKLVDMLKSH 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_031524.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..97		13/26 (50%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	88..110		17/21 (81%)
		bZIP_ATF3	96..149	CDD:269870	29/52 (56%)
		coiled coil	96..146	CDD:269870	27/49 (55%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	114..142		14/27 (52%)
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	6/12 (50%)
Atf3	NP_001259125.1	coiled coil	215..265	CDD:269870	6/12 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833407
Domainoid	1	1.000	75	1.000	Domainoid score	I9036
eggNOG	1	0.900	-	-		E1_KOG1414
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003423
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23351
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5873
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.960