Protein Alignment Arx and ey

DIOPT Version :9

• Sequence 1: NP_001292869.1
• Gene: Arx / 11878
• MGIID: 1097716
• Length: 564
• Species: Mus musculus
• Sequence 2: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Alignment Length: 595
• Identity: 130/595 - (21%)
• Similarity: 206/595 - (34%)
• Gaps: 225/595 - (37%)

Mouse    13 RPECKSKSPTLLSSYCIDSILGR---RSPCKMRLLGAAQS--LPAPLASRADQEKAMQGSPKSSS 72
            || |.......:|:.|:..||||   ....:.|.:|.::.  ..|.:.|:..|.|      :...
  Fly   131 RP-CDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYK------RECP 188

Mouse    73 APFEAELHLPPKLRRLYGPGGGRLLQ---------------------------------GAAAAA 104
            :.|..|:.             .||||                                 |:::.:
  Fly   189 SIFAWEIR-------------DRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTS 240

Mouse   105 AAAAAAAAAATATG------TAGPRGEVPPPPP--PAARPGERQDSAGAVAAAAAA---AAWDTL 158
            |..:.:|..:.:.|      .:|.||.:.....  ..|.|....:|.||..:...:   |.::.|
  Fly   241 AGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKL 305

Mouse   159 KI-------------------------------SQAPQVSISRSKSYRENGAPFVPP-------- 184
            ::                               |..||:.....::.:::.....||
  Fly   306 RLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWY 370

Mouse   185 PPALDEL---SGPGGVAHPEERLSAASGPGSAPAAGGGTGAEDDEEELLEDEEDEEEEEELLEDD 246
            |.:|.|:   |.|        .:::.:...|.|:........:|.|.|
  Fly   371 PTSLSEIPISSAP--------NIASVTAYASGPSLAHSLSPPNDIESL----------------- 410

Mouse   247 DEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGK-DGE 310
                      |.:...|.|.|||.                   ::..|:||..|..|..|. :||
  Fly   411 ----------ASIGHQRNCPVATE-------------------DIHLKKELDGHQSDETGSGEGE 446

Mouse   311 DSVCLSAGS--------DSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRL 367
            :|   :.|:        |....:||||.:|.||:||:.|::.||:.|::|||||||.||.||.::
  Fly   447 NS---NGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKI 508

Mouse   368 DLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAW 432
            .|.|||:||||.|||||||:.||...|...|                              :|..
  Fly   509 GLPEARIQVWFSNRRAKWRREEKLRNQRRTP------------------------------NSTG 543

Mouse   433 TAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSAS 497
            .:|.:::.:|..||...|.|.|        ..|:.|..:          |.|...||:..|:|.|
  Fly   544 ASATSSSTSATASLTDSPNSLS--------ACSSLLSGS----------AGGPSVSTINGLSSPS 590

Mouse   498 TAAALLRQPT 507
            |.:..:..||
  Fly   591 TLSTNVNAPT 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arx	NP_001292869.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..79		4/24 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..264		28/205 (14%)
		Homeobox	334..386	CDD:278475	32/51 (63%)
		OAR	528..545	CDD:281777
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	532..545
ey	NP_001014693.1	PAX	98..221	CDD:128645	21/109 (19%)
		Homeobox	475..527	CDD:278475	32/51 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910