DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnd2 and Rac1

DIOPT Version :9

Sequence 1:	NP_033838.1	Gene:	Rnd2 / 11858	MGIID:	1338755	Length:	227	Species:	Mus musculus
Sequence 2:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster

Alignment Length:	169	Identity:	75/169 - (44%)
Similarity:	114/169 - (67%)	Gaps:	1/169 - (0%)

- Green bases have known domain annotations that are detailed below.

Mouse     9 KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRP 73
            |.|||||...|||.||..:..:|:||.|:||||:||:|:..:|.:.|.|.:|||:|...||.:||
  Fly     5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRP 69

Mouse    74 LAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRL 138
            |:||.:|..||||.:..|.:.::|..||..|.:..||:..::|||.|||:|.|..|:.:|..::|
  Fly    70 LSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKL 134

Mouse   139 IPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVA 177
            .|:|:.||..:||::|||.|:|||: .:::.::.||..|
  Fly   135 APITYPQGLAMAKEIGAVKYLECSA-LTQKGLKTVFDEA 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnd2	NP_033838.1	Rnd2_Rho7	7..227	CDD:206736	75/169 (44%)
		Effector region. /evidence=ECO:0000255	36..44		5/7 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..227
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	75/169 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810