DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arhgdib and RhoGDI

DIOPT Version :9

Sequence 1:	NP_001288230.1	Gene:	Arhgdib / 11857	MGIID:	101940	Length:	200	Species:	Mus musculus
Sequence 2:	NP_001262080.1	Gene:	RhoGDI / 40179	FlyBaseID:	FBgn0036921	Length:	201	Species:	Drosophila melanogaster

Alignment Length:	202	Identity:	97/202 - (48%)
Similarity:	131/202 - (64%)	Gaps:	6/202 - (2%)

- Green bases have known domain annotations that are detailed below.

Mouse     1 MTEKDAQPQLEEADDDLDSKLNYKPPPQKSLKELQEMDKDDESLTKYKKTLLGDV---PVVADPT 62
            |.|.:.:...|..|||:.. .||:.||:|:::|:...|::||||.:||:.|||..   .::.:|.
  Fly     1 MAETETKHHPEHHDDDVHD-ANYQAPPEKTIEEIMAADQEDESLRRYKEALLGAAQTEKIIVEPN 64

Mouse    63 VP-NVTVTRLSLVCDSAPGPITMDLTGDLEALKKDTFVLKEGIEYRVKINFKVNKDIVSGLKYVQ 126
            .| .|.|.:|:||.:.. ..:.:||||||..|||..||:|||::|:|:|:|.|.::||.||||||
  Fly    65 DPRKVIVKKLALVVEGR-DDMELDLTGDLSQLKKQLFVIKEGVQYKVRIDFIVQREIVHGLKYVQ 128

Mouse   127 HTYRTGMRVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLTWEWN 191
            .|.|.|:.|||...|||||.|:.|...:|||.||||.|..:||||...|.||||||..||.|:|.
  Fly   129 KTSRLGVNVDKMKHMVGSYPPKKEIQFYLTPAEEAPSGTFSRGTYSVSSVFTDDDKHIHLEWDWT 193

Mouse   192 LAIKKDW 198
            ..|||||
  Fly   194 FEIKKDW 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arhgdib	NP_001288230.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..39		12/37 (32%)
Arhgdib	NP_001288230.1	Rho_GDI	7..197	CDD:366924	92/193 (48%)
RhoGDI	NP_001262080.1	Rho_GDI	14..199	CDD:280310	91/186 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837037
Domainoid	1	1.000	195	1.000	Domainoid score	I3138
eggNOG	1	0.900	-	-		E1_KOG3205
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3780
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54245
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001289
OrthoInspector	1	1.000	-	-		otm42349
orthoMCL	1	0.900	-	-		OOG6_102354
Panther	1	1.100	-	-	LDO	PTHR10980
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2126
SonicParanoid	1	1.000	-	-		X792
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.790