Protein Alignment Ranbp16 and Ranbp17

DIOPT Version :10

• Sequence 1: NP_001188596.1
• Gene: Ranbp16 / 118436
• FlyBaseID: FBgn0053180
• Length: 1110
• Species: Drosophila melanogaster
• Sequence 2: NP_001349804.1
• Gene: Ranbp17 / 66011
• MGIID: 1929706
• Length: 1108
• Species: Mus musculus
• Alignment Length: 1100
• Identity: 583/1100 - (53%)
• Similarity: 777/1100 - (70%)
• Gaps: 41/1100 - (3%)

  Fly     3 IQQLEVLCKQLYEATDIRIRSEAEKALVTFVSSQDALPKCQLLLQRADSSYAQLLAASTLTKL-- 65
            :.:|||||..||..||:..|.||||||:..:.|.:.|.||||||::..:||||||||:.|:||
Mouse     8 LAELEVLCTHLYVGTDLTERIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVT 72

  Fly    66 -IQGLSLQERIDIRSYALNYLATVPNLQHFVVQALVSLLAKLTKYGWFDSYKEEMVFQNLLEDVK 129
             |..|.:::|||||:|.|||:|:.|.|..||:|||:.::|||||.|||:..|:|.||:.::.|||
Mouse    73 RINPLPIEQRIDIRNYILNYVASQPKLAPFVIQALIQVIAKLTKLGWFEVQKDEFVFREIIADVK 137

  Fly   130 KFLQGSVEHCTIGVQILSQLVCEMNSVVEMDVQVSFSKMRKIATSFRDQQLLETFLLSCSLLVSA 194
            |||||:||||.|||.||.:|..|||.|   |.....:|.|||||||||..|.:..:|:||||...
Mouse   138 KFLQGTVEHCIIGVIILCELTQEMNLV---DYSRPSAKHRKIATSFRDTSLKDILVLACSLLKQV 199

  Fly   195 RDNSKNISFMDESQQALISHVLRLTKNCLSFDFIGSSTDESADDMNNVQIPTAWRPAFLDSNTLK 259
            .  :|.::..|:.||:|:..||:|..:||:|||:|||.||||||:..|||||.||..||:..||.
Mouse   200 L--AKPLNLQDQDQQSLVMQVLKLVLSCLNFDFLGSSADESADDLCTVQIPTTWRTIFLEPETLD 262

  Fly   260 LFFDLYQILPNGLASYSISCLVQITSVRRSLFNNSERTKFLTHLVEGVKDILTTLHGLSDPDNYH 324
            |||:||..||..|:..::|||||..|.|||||::.||.|:|.:|::|||.||....|||||.|||
Mouse   263 LFFNLYHSLPPLLSQLALSCLVQFASTRRSLFSSPERAKYLGNLIKGVKRILENPQGLSDPGNYH 327

  Fly   325 EFCRLLARLKSNYQLGELIAVPCYPEAIQLIAKFTVESLHLWLFAPNSVHYLLTLWQRMVASVPY 389
            ||||.|||||:|||||||:.|..|.|.|.|||.||:.||..|.|||||||||||||||||||||:
Mouse   328 EFCRFLARLKTNYQLGELVLVKEYAEVIGLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPF 392

  Fly   390 VKSPDPHLLGTYTPEVIKAYIESRLDAVPVIIRDNLDDPLDDFCMVQQQLEQLSVIERCEYNKTC 454
            |||.:||||.||.||:.||:|.|||::|.:::||||:|||||...|.||||||..:.||||.|||
Mouse   393 VKSAEPHLLDTYAPEITKAFITSRLESVAIVVRDNLEDPLDDTATVFQQLEQLCTVSRCEYEKTC 457

  Fly   455 NLLVQHFDQKAREYENLLQTPNANSIDITIHELQLTWLVYIIGSAIVGRLTVATSDEHDTMDAEL 519
            .||||.|||.|:.|:.||......::|:.|.|.:|.||:|::|:.:.||||..::||||.||.||
Mouse   458 TLLVQLFDQNAQNYQKLLHAAPGLAVDMAIQEGRLAWLIYLVGTVVGGRLTYTSTDEHDAMDGEL 522

  Fly   520 VIRVLQLMTLTDARLPQAGCEKLELAILSFLDQVRKMHSSEQAQKAN------------------ 566
            ..||.||::|.|.|||....||:|||:|.||||.||.:..:|.|:.:
Mouse   523 SCRVFQLISLMDTRLPHCTNEKIELAVLWFLDQFRKTYVGDQLQRTSKVVRPKNDVSRVPEKAWK 587

  Fly   567 ---LNKRLSEVFGLTDEQMLLSFINRKIITNLKFWGRSESIITKTLMLLSELSVHFNSVRKLARL 628
               :..|:|||.|:||:..:|.....||:||||:|||.|.:|::||..||:|||.:..::||.::
Mouse   588 IVKVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRCEPVISRTLQFLSDLSVGYILLKKLVKI 652

  Fly   629 EEVQFMLTHHTSEHFPFLGTNS--SLSEMRCRTMFYTSLGRLLMFDLGEDEERFYNFLEPLTNQF 691
            :.|:|||.:||||||||||.:.  ::.:.||||.|||:|.||||.||||||:.|.||:.|||..|
Mouse   653 DAVKFMLKNHTSEHFPFLGISETYNVGDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVSF 717

  Fly   692 ESLGSVMMDNNIFSNEEAKKVIIGLARDLRGLALPLNARIQYTMLFEWLYYADYLPILLRAMDLW 756
            |::  :.:.||.|..||.|:::|||||||||:|..||.:..|||||:|:|.| |||:|.||::.|
Mouse   718 ETV--LQIFNNNFKQEEVKRMLIGLARDLRGIAFALNTKTSYTMLFDWIYPA-YLPVLQRAIERW 779

  Fly   757 AHDPAVTTPILKLFAELVHCRTQRLAGNVSSPMGILLFREASKLICIYGNRILH-QEVPRERLYP 820
            ..:||.|||||||.|||:..|:|||..:||||.||||||||||:||.|||:||. ..:.::::||
Mouse   780 YGEPACTTPILKLLAELMQNRSQRLNFDVSSPNGILLFREASKMICTYGNQILSLGSLSKDKIYP 844

  Fly   821 MRLKGIAICFLILKNSLGGNYVNCGVFKLYGDDTLDSVLNIIAKLILTIEQRDLIEYPKLSTAYY 885
            |:||||:||:..||::|.||||:.||||||||:..|:||....|::|::...||::|.|||.:||
Mouse   845 MKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYY 909

  Fly   886 NLLNCLSQDHVSYLAALEPAAFVYILKSLTKGLAALDSATYISCCTILDSIVSYIFKQLQMKVST 950
            .||.||:|||:|::..|||...:|:|.||::||..||:....||||.||.:|:|:||.:..:
Mouse   910 PLLECLTQDHMSFITNLEPPVLLYVLTSLSEGLTTLDTVVSSSCCTSLDYMVTYLFKHIAKE--- 971

  Fly   951 FPNKKLRSLN--QENVQFLKVVEMNSELLQSMMSSLLNNVLQEDCRNQWSMSRPLLVLILLYEDY 1013
             ..|.|||..  |...:.|..::.|.::||.|||.|:|.::.||||||||:|||||.||||.|.|
Mouse   972 -GKKPLRSREAMQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKY 1035

  Fly  1014 YRSLKDRIICAQPIEKQQTMAQWFDDLMVGIERNVSSKNKEKFTQNMSTFRRDVVNLPKS 1073
            :..|:..:|.:||:.||:.:.|.|.:||.|:|:|:|.||:::||||:|.|||||....:|
Mouse  1036 FSELRASLINSQPLPKQEVLGQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRS 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ranbp16	NP_001188596.1	IBN_N	25..87	CDD:197981	35/64 (55%)
Ranbp17	NP_001349804.1	CRM1	8..>167	CDD:227432	89/161 (55%)
		IBN_N	30..95	CDD:197981	35/64 (55%)