DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arc and Arc1

DIOPT Version :9

Sequence 1:NP_001263613.1 Gene:Arc / 11838 MGIID:88067 Length:396 Species:Mus musculus
Sequence 2:NP_610955.1 Gene:Arc1 / 36595 FlyBaseID:FBgn0033926 Length:254 Species:Drosophila melanogaster


Alignment Length:212 Identity:49/212 - (23%)
Similarity:82/212 - (38%) Gaps:35/212 - (16%)


- Green bases have known domain annotations that are detailed below.


Mouse   186 QESVEAQQYQSWGPGEDGQPSPGVD-----------TQIFEDPR------EFLSHLEEYLRQVGG 233
            :|.:||.:..:.|.......:.|.|           |..|...|      ||:.::|.|....|.
  Fly    13 RELIEAVRAAAVGAAGSAAAAGGADASRGKGNFSACTHSFGGTRDHDVVEEFIGNIETYKDVEGI 77

Mouse   234 SEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVE----FKKEFLQYSEGTLSREAIQRELEL---P 291
            |:|..|..|.....|.|..||:..:.....|.|    .::.|      :.::.|.|..:|.   .
  Fly    78 SDENALKGISLLFYGMASTWWQGVRKEATTWKEAIALIREHF------SPTKPAYQIYMEFFQNK 136

Mouse   292 QKQGEPLDQFLWRKRDLYQTLYVDAEEEEI-IQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEV 355
            |...:|:|.|:.:||.|...|.....:||. :..:.|.|..|.::.:......|.:.|:::|..:
  Fly   137 QDDHDPIDTFVIQKRALLAQLPSGRHDEETELDLLFGLLNIKYRKHISRHSVHTFKDLLEQGRII 201

Mouse   356 ----QDGLEQAAEPSGT 368
                |:..||.|....|
  Fly   202 EHNNQEDEEQLATAKNT 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ArcNP_001263613.1 Interaction with SH3GL1 or SH3GL3. /evidence=ECO:0000250|UniProtKB:Q63053 89..100
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 177..207 4/20 (20%)
Interaction with DNM2. /evidence=ECO:0000250|UniProtKB:Q63053 195..214 4/29 (14%)
Arc_C 278..360 CDD:375599 20/89 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 356..396 5/13 (38%)
Arc1NP_610955.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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