DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ap3s2 and AP-1sigma

DIOPT Version :9

Sequence 1:	NP_033812.3	Gene:	Ap3s2 / 11778	MGIID:	1337060	Length:	193	Species:	Mus musculus
Sequence 2:	NP_001247273.1	Gene:	AP-1sigma / 42835	FlyBaseID:	FBgn0039132	Length:	157	Species:	Drosophila melanogaster

Alignment Length:	151	Identity:	55/151 - (36%)
Similarity:	100/151 - (66%)	Gaps:	6/151 - (3%)

- Green bases have known domain annotations that are detailed below.

Mouse     1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIY 65
            |:..:|:|:..||.||.::|..:|::::::|.||....:|.|...:|:|||      ..|.|::|
  Fly     1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLE------WKDCKIVY 59

Mouse    66 RHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVL 130
            :.||:|||...::.:::||..|::|..:||.|||.|.:|||||:||:.:|.::||.|:::||.:.
  Fly    60 KRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQ 124

Mouse   131 ETNMNEIVAQIEAQNRLEKSE 151
            ||:...::..|.:|:.|::.|
  Fly   125 ETSKKNVLKAIASQDLLQEDE 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ap3s2	NP_033812.3	AP3_sigma	1..146	CDD:341438	53/144 (37%)
AP-1sigma	NP_001247273.1	AP1_sigma	4..145	CDD:341435	53/146 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53551
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820