Protein Alignment AP3S1 and AP-2sigma

DIOPT Version :10

• Sequence 1: NP_001351048.1
• Gene: AP3S1 / 1176
• HGNCID: 2013
• Length: 209
• Species: Homo sapiens
• Sequence 2: NP_650961.2
• Gene: AP-2sigma / 42525
• FlyBaseID: FBgn0043012
• Length: 142
• Species: Drosophila melanogaster
• Alignment Length: 148
• Identity: 60/148 - (40%)
• Similarity: 93/148 - (62%)
• Gaps: 6/148 - (4%)

Human     1 MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIY 65
            ||:.|||.|..||.||:|:|..:.:|.:|::|.|...:|:.||....||:|      ..:.|::|
  Fly     1 MIRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVE------FRNFKIVY 59

Human    66 RHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVL 130
            |.||.|||..|||.:::.|..|:.|..|||.|::.|.|||||||:|:..||::::.||.:.|.:.
  Fly    60 RRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIR 124

Human   131 ETNMNEIVTQIDAQNKLE 148
            ||:..:::.|:...|.||
  Fly   125 ETSQTKVLKQLLTLNSLE 142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP3S1	NP_001351048.1	AP3_sigma	1..146	CDD:341438	57/144 (40%)
AP-2sigma	NP_650961.2	AP2_sigma	1..141	CDD:341437	58/145 (40%)