Protein Alignment TWIST2 and sc

DIOPT Version :10

• Sequence 1: NP_476527.1
• Gene: TWIST2 / 117581
• HGNCID: 20670
• Length: 160
• Species: Homo sapiens
• Sequence 2: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Alignment Length: 144
• Identity: 40/144 - (27%)
• Similarity: 65/144 - (45%)
• Gaps: 37/144 - (25%)

Human    31 RKRRYSKK-------SSEDGSPTPGKRGKKGSPSAQSFEELQS-QRILANVRERQRTQSLNEAFA 87
            :.|:|:.:       |....|.:||     .||:..:.::.|| ||  .|.|||.|.:.:|.:||
  Fly    63 KTRKYTPRGMALTRCSESVSSLSPG-----SSPAPYNVDQSQSVQR--RNARERNRVKQVNNSFA 120

Human    88 ALRKIIPTL------------PSDKLSKIQTLKLAARYIDFLYQVLQSDEM--------DNKMTS 132
            .||:.||..            |..|:||:.||::|..||..|..::  |::        :|.:|.
  Fly   121 RLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLV--DDLNGGSNIGANNAVTQ 183

Human   133 CSYVAHERLSYAFS 146
            ......|..|::.|
  Fly   184 LQLCLDESSSHSSS 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TWIST2	NP_476527.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		8/38 (21%)
		bHLH_TS_TWIST2	51..132	CDD:381543	30/101 (30%)
sc	NP_476803.1	bHLH_TS_dAS-C_like	100..166	CDD:381587	25/67 (37%)