Protein Alignment Prdx6 and Prx4

DIOPT Version :10

• Sequence 1: NP_031479.1
• Gene: Prdx6 / 11758
• MGIID: 894320
• Length: 224
• Species: Mus musculus
• Sequence 2: NP_525002.1
• Gene: Prx4 / 53577
• FlyBaseID: FBgn0040308
• Length: 242
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 58/207 - (28%)
• Similarity: 90/207 - (43%)
• Gaps: 25/207 - (12%)

Mouse     6 LLGDEAPNFE----ANTTIGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNV 66
            ::...||.||    .|..|.::....:|| .:.:|..:|.|||.||.||:...:....||.|...
  Fly    51 VISKPAPQFEGTAVVNKEIVKLSLSQYLG-KYVVLLFYPLDFTFVCPTEIIAFSDRIAEFKKIKT 114

Mouse    67 KLIALSIDSVEDHLAWSKDINAYNGETPTEKLPFPIIDDK----GRDLAILLGMLDPVEKDANNM 127
            ::|.:|:||...||||   ||....|.....:..|::.|.    .:|..:.|      |...:.:
  Fly   115 EVIGVSVDSHFTHLAW---INTPRKEGGLGDVKIPLLSDLTHKISKDYGVYL------ESSGHAL 170

Mouse   128 PVTARVVFIFGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTGTKPVATPVDWKKGESVMVVPT 192
                |.:||......|:...:.....||:.||.:|:|.:.|.|.|.....|..|:.|... :||
  Fly   171 ----RGLFIIDQTGVLRQITMNDLPVGRSVDETIRLVQAFQYTDTHGEVCPAGWRPGADT-IVP- 229

Mouse   193 LSEEEAKQCFPK 204
             :.||..:.|.|
  Fly   230 -NPEEKTKYFAK 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prdx6	NP_031479.1	PRX_1cys	7..222	CDD:239314	58/206 (28%)
		Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000250|UniProtKB:O35244	31..40		1/8 (13%)
Prx4	NP_525002.1	PRX_Typ2cys	52..223	CDD:239313	51/184 (28%)