DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RacGAP84C and arhgap32

DIOPT Version :9

Sequence 1:	NP_476704.1	Gene:	RacGAP84C / 117503	FlyBaseID:	FBgn0045843	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_004916221.2	Gene:	arhgap32 / 734056	XenbaseID:	XB-GENE-1002474	Length:	1995	Species:	Xenopus tropicalis

Alignment Length:	297	Identity:	68/297 - (22%)
Similarity:	115/297 - (38%)	Gaps:	77/297 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 FGSQSLDSLQDRV----------------DMNPSG---------CDGLSTDGLDFCSQ--SHSGL 83
            |.|:.::.:.|:|                .|.|:.         .|.| ..|...||:  |||.|
Frog   315 FPSECVELINDKVPQSMTNSVPKPVSPAHGMRPASWSYFPPYLEMDSL-RPGTSCCSEVLSHSQL 378

  Fly    84 ---LREHNFKIKSYYYNVGNCVHCRKRIRFAMASLRCRACPLRCHI---GCCRQLTVNCIPQPQI 142
               .|:|.                 |.|.|....::.|  |.:..:   |..|:....|
Frog   379 SSVSRKHG-----------------KLITFLRTFMKSR--PSKQKLKQRGILRERVFGC------ 418

  Fly   143 GTKRGCLSDYAPRVAPMVPALIVHCVTEIEARGLQQEGLYRVSSTREKCKRLRRKLLRGKSTPHL 207
                 .|.::.......||.::..|...||..|: .:|:||:|......::||.: ...:..|.|
Frog   419 -----DLGEHLLNSGQDVPQVLRSCTEFIEKHGI-VDGIYRLSGIASNIQKLRHE-FDSEQIPDL 476

  Fly   208 GN----KDTHTLCCCVKDFLRQLVHPLI--PIYHR-RDFEEATRHEDRLAVEMAVYLAVLELHQA 265
            ..    :|.|.:....|.:.|:|.:||:  .:|.: .|...|...|:||   :.::..:.:|...
Frog   477 TKDVYIQDIHCVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERL---VKIHDVIQQLPPP 538

  Fly   266 HRDTLAYLMLHWQKIAESPAV-RMTVNNLAVIFAPTL 301
            |..||.:||.|..::|...:: .|...|||:::||.|
Frog   539 HYRTLEFLMRHLSRLATYCSITNMHTKNLAIVWAPNL 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RacGAP84C	NP_476704.1	C1_1	87..139	CDD:278556	9/54 (17%)
RacGAP84C	NP_476704.1	RhoGAP_MgcRacGAP	142..330	CDD:239847	43/168 (26%)
arhgap32	XP_004916221.2	PX_RICS	131..245	CDD:132831
		SH3_ARHGAP32_33	267..320	CDD:212769	2/4 (50%)
		RhoGAP_CdGAP	414..608	CDD:239849	44/178 (25%)
		ZipA	<1758..>1898	CDD:225657
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910